Chapter 451: Artemisinin's embarrassment


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Artemisinin is undoubtedly the pride of the Chinese. Tu Youyou also won the Lasker Award and the Nobel Prize for this, which proves that the Chinese can also make some achievements in the field of medicine. However, in application, artemisinin The situation is very embarrassing. ┏Ⅹ④③⑨⑨┛
China's development time is too short. At the beginning, it did not understand international business rules. In addition, the high threshold established by international pharmaceutical giants made it very difficult for domestic artemisinin drugs to enter the international market. In 1994, Nova took the opportunity to purchase the international sales rights of artemisinin compound drugs from the original patent holder of artemisinin at a low price. After five years of development, it became the first in the world to launch a fixed dose of artemisinin Pharmaceutical companies with compound or combined medications.
Soon after, the World Health Organization recommended the use of compound artemisinin as the first antimalarial drug. Unfortunately, no Chinese pharmaceutical company complies with GMP (World Health Drug Production Quality Management Standards), so Novartis became the only qualified supplier at that time and obtained a compound artemisinin derivative patent.
Since then, French Sanofi has also obtained some related patents and launched its own artemisinin drugs, which has led to the international artemisinin market being monopolized by Nova, Sanofi and Indian generic drugs, and foreign pharmaceutical giants occupying the international Artemisinin medicines account for more than 90% of the market, while China's artemisinin medicines account for less than 10%.
This does not match the status of China's artemisinin inventing country and the main producer of absolute raw materials. China has become an artemisinin raw material producer and can only earn meager profits under the squeeze of international pharmaceutical giants.
Moreover, because Nova and Sanofi monopolized the artemisinin market, they not only have the pricing power of related drugs, but also continue to squeeze the purchase price of artemisinin raw materials, resulting in the continuous decline in the price of artemisinin raw materials. Most of the profits of the vegetarian industry are taken by Nova and Sanofi, and only a little leftovers are left for the domestic distribution.
"The entry standards for the pharmaceutical industry can be said to have been set by those multinational pharmaceutical giants. We want to enter. It must be difficult; in fact, no matter which line is similar, the digital industry is also the same, mobile phones, computers, playback terminals, etc., rules and standards They are all monopolized by developed countries, and it is very difficult for our enterprises to enter. "Shen Long said," But there are some things that you never have a chance if you don't do it. There is hope only if you do it. "
Isn't this the case with the home appliance and mobile phone industries? Afterwards, Chinese companies have gradually caught up with and even surpassed those in Europe, America, Japan and South Korea. They have a certain voice in the standard-setting meetings. In the future, they have launched advanced mobile phones that are leading foreign companies. But we occupy the world's largest market and have unique patents in the world, not without all opportunities.
"Yeah, hope this will be a good start." Director Qiao sighed, "What are you going to do next?"
"Be the first, let the people in the world know that we have made what they failed to achieve, and then through Ron they provoke public opinion in the United States, through the PR company to expand the impact, prompting the FDA to accept our review request, Carry out clinical trials. "Shen Long said.
"I don't know much about the situation in the United States, but it sounds like you are very careful and professional. If you need any help, just open your mouth." Director Qiao is very pleased. "Accordingly, you are fully qualified for this achievement. The Nobel Prize, but whether it can be won or not is hard to say. The Western scientific community has always been biased against traditional Chinese medicine. "
It would be great if he could win the prize in a short time. Using the influence of the Nobel Prize can undoubtedly speed up the FDA review, but Shen Long thought that Tu Youyou invented artemisinin in the 1970s, but waited until The award was only awarded in 2015. Even if you can win the award, you will have to wait a long time.
Shen Long spent several days writing the paper and delivering it to the New England Journal of Medicine. This paper immediately shocked the magazine. They quickly distributed it to authorities in related fields for review, and then published it in the fastest time.
The first publication of the paper caused uproar in the global medical community. The new drug originally introduced by Shen Long to treat leukemia is only known to Chinese medical practitioners, but nowadays, it is almost known all over the world.
Many authoritative persons in this field have rushed to Modu and came to Shenlong ’s medical hall and pharmaceutical factory to learn about the latest progress. When they saw a patient ’s improved medical record, they were all stunned. This result means As a result, humans have conquered a terminal illness. They have not thought that this disease will be conquered, but they did not expect that it would be a Chinese doctor who made this achievement, and the traditional Chinese medicine method was adopted.
"Incredibly, the condition of these patients is really under control, and it is still getting better." A senior professor from Hopkins University looked at the data just detected and said with emotion, "Cheng, you made a great Achievements. "
"This is not the result of my own hard work, but the glory of traditional Chinese medicine." Shen Long did not monopolize this credit, "And Professor Ma Lin, Director Qiao, Mr. Weng and many other colleagues also provided me a lot of help . "
"Cheng ~ EbookFREE.me ~ Such a powerful drug should be used by patients all over the world. Are you now ready to apply for FDA review?" Professor at Harvard Medical School said excitedly, and the pharmaceutical giant bribed Academia is a common thing, but it does not mean that every medical authority is under their control. "If you have this plan, I am willing to help you."
"Now the production scale of the main raw materials is limited, and even domestic demand cannot be fully resolved. I think it may be possible to wait." Shen Long did not act too eagerly. "And, as far as I know, Chinese medicines want to It seems very difficult to pass the FDA review. "
"Cheng, science should not have borders. American patients also need this medicine." Professor Harvard advised, "As for the FDA review, I have extensive experience in this area."
Not only scholars but also representatives of pharmaceutical companies came to find Shen Long. It was not just Nova that came back. These companies either threatened or lured, and wanted to get this kind from Shen Long. Patent of medicine.
"Global patent use rights are impossible, and overseas patent use rights other than China are not possible. You should change some more realistic conditions!" As said before, Shen Long is also a bit Do not want to repeat the mistakes of artemisinin.
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