Chapter 192:

The proposal of Zhenzhe's management as the first batch of clinical volunteers for HPV vaccine was proposed by Zheng Lingling. Li Zheng, Liu Sichao, Zhang Chao and other project workers couldn't wait to try the vaccine effect on themselves as early as the end of the biological experiment.
When Zheng Lingling saw a group of big men injecting HPV vaccine into her body, she made no secret of her disgust, and suggested that she was willing to receive the vaccine, but Li Zheng stopped it.
Li Zheng prepared for the worst. In case this drug clinic really fails to recruit volunteers, they will have to be on top of it. Zheng Lingling, this precious woman, should keep it.
Just before Li Zheng came to make the last attempt, Zheng Lingling told him that Zhenzhe's management was unanimously willing to be the first batch of volunteers for the HPV vaccine.
Li Zheng said that he was not moved. It must be a fake. Zhenzhe’s management, except for the three or four people from the original Li Zheng laboratory, are new colleagues. New colleagues can make such a decision. This is for Li Zhengji. Great trust.
Li Zheng's words were loud and loud, especially the last sentence, which made the whole conference room commotion again.
In foreign countries, it is not uncommon for researchers to test drugs on their own. For example, in the past hepatitis B vaccine, its clinical road was twists and turns. When it was first submitted to the FDA, the FDA rejected its application.
The staff of the vaccine project injected themselves, followed by people around them, and it spread slowly. It took a few years for the FDA to officially approve the clinical application for this project.
In China, this seems to be an amazing thing. The gazes of all the older generations who looked at Li Zheng instantly changed. They knew that Professor Li had extraordinary accomplishments in pharmacy, but they didn't expect that besides his academic level, this person's ideological and moral heights were even more amazing.
In order to develop a vaccine to prevent cervical cancer, expose yourself to the HPV virus. This is risking your life to do research!
Everyone felt that the documents at hand had become a bit heavy.
Fans in the Yanjing Hotel were still rustling, and a group of biology scholars took out the pens in their chest pockets and began to write and draw on the materials, and they began to seriously evaluate the clinical feasibility of this project.
Li Zheng's dignified expression slowed down a bit, and he was willing to take it seriously, for fear that you would reject it without looking.
Time passed by, except for the sound of the fan, but the sound of pages turning was heard in the conference room.
"What are the old men doing in there? We are going to get off work." Outside the meeting room, several aunts in their forties gathered together.
The state-run guest house is not like the 24-hour smiling service in the hotels of later generations. When it's time for get off work, a group of old men still stay in the meeting room, which can make these aunts unhappy. They still want to go home early to rest.
"How about we go in and remind you?"
"Go, go, if it weren't for the older people in it, I would just go straight in and blow them away!" someone said.
So these bigwigs, who are among the best in Chinese biology, encountered the most embarrassing thing in their lives.
A few middle-aged aunts dressed in the costumes of Yanjing Hotel service staff walked into the meeting room with their hips akimbo, and said in Beijing dialect with a strong accent: "It's off work, it's off work, we all have to get off work, you change place Reading."
Everyone was startled at first, and then they didn't know who started, and there was a burst of huge laughter.
Old Yang suppressed his smile and stood up with a dry cough, "Okay, sister, let's change places now." He said hello to everyone.
The big guys all smiled, and while taking things neatly, they smiled and apologized to a few service staff, "I'm sorry, big girl, I have delayed your get off work."
By the time the leaders of Yanjing Hotel hurried over, half of the big men stepped out of the gate of Yanjing Hotel.
This time the meeting room was set by Yang Lao. The cold sweat on the leader's forehead kept spreading out. He just forgot to say one more thing. How could this happen.
You know, although these people are not high-ranking officials with real power, many of them are above the main hall, and these experts and scholars are all able to reach the heavens.
"Old Yang, this..."
"It's okay, we are wasting your time, don't worry about it."
"but……"
"No need." Old Yang patted the leader on the shoulder, then smiled and walked outside the door.
Everyone didn't pay attention to this matter at all, and even some people thought it was interesting, and there was another joke after the meal.
After this meeting, the drug control department had a three-month debate on whether to approve the HPV vaccine clinical application. On August 1, 1990, the first vaccine-based original drug was conducted in Huajing. Drug clinical.
Professor Li Zheng, the first biologist in the middle age of China, injected the HPV vaccine into his body under the live broadcast of CTV, and demonstrated the safety of the vaccine with facts.
"The first batch of 50 people in the clinic, 17 people have signed up so far, 8 of them are too poor, expecting the fees for the trial drugs. The other 9..." Zhang Chao paused, with a strange expression on his face. "The other 9 are all students from the biology departments of various universities in Huajing. They admire you very much. Some people even suggest that you don't need to pay for the test medicine, just meet you."
Li Zheng was stunned for a moment, then smiled. He also enjoys idol treatment?
However, Li Zheng only understood a few days later what a real idol effect is.
Li Zheng originally planned to officially start the first clinical trial of the drug on August 15th, half a month after the approval order, and then seeing the time getting closer, the first batch of 50 places has never been full.
Zhang Chao was anxious, and when he contacted Xiangjiang, he couldn't help but confide in a few words, which reached Zhou Sitian's ears.
Without saying anything, Zhou Sitian came to the interior without telling Li Zheng and publicly announced as a clinical volunteer for HPV vaccine as a star of Xiangjiang.
At this moment, both Xiangjiang and Inland shook.
It is said that the influence of the little fresh meat of later generations is great, but in terms of influence, the influence of the Xiangjiang jade female stars in the 1980s and 1990s is definitely not inferior to the later generations of little fresh meat, or even higher.
Zhou Sitian’s public registration has attracted many Xiangjiang people to rush to Huajing to participate in HPV vaccine clinical trials, as well as in the mainland. Not long after the news spread, these 50 places were full, and there were even people who stayed in front of the hospital. Must participate. The staff repeatedly persuaded them and refused to leave.
"Sister, your influence is really great." Li Zheng couldn't help sighing after seeing the full quota two hours after the news spread.
"I have seen the information. Cervical cancer is the second most common tumor in women after breast cancer. If I can contribute to the elimination of cervical cancer, it will benefit me publicly and privately." Zhou Sitian smiled. Said.
There was a softness in Li Zheng's eyes. His sister, that's it, her mouth refused to admit that she made this decision because she loved her younger brother. She used her life safety to seek a false name. Zhou Sitian has never been this way. Kind of people.
"Sister, thank you." Li Zheng said softly.
Zhou Sitian glanced at him, "It’s better to take care of yourself if you say thank you. I didn’t like Liang Zhe all day long. I didn’t like Liang Zhe, but now I think it’s him. Otherwise, who can stand you? !"
Li Zheng...
Thanks to Zhou Sitian’s influence, the clinical trials of the first batch of 50 volunteers started smoothly, and the clinical trials went very smoothly. After 50 volunteers were injected with HPV vaccine, 100% of the subjects produced anti-HPV virus. It also reduced the risk of subjects with a single exposure and HPV infection by 94%, and 86% of people were still protected from six exposures and HPV without being infected.
As soon as this result came out, everyone was very excited. A group of biologists including Yang Lao also paid great attention to this clinical trial. After all, if it succeeds, this HPV vaccine can be called the first to a certain extent. Anti-cancer vaccine.
With the full cooperation of the drug management department, on October 25, 1990, the second drug clinical trial was launched in Huajing First Hospital.
This time, the scale was expanded, and the number of participants in the experiment reached 200, which is the largest scale in the history of Chinese drug clinical trials.
With more people, there will be more things. The old man’s words are not fake at all. This time, Li Zheng’s luck was obviously not so good. On November 6, 1990, the first death case in the history of Huaguo drug clinical trials was born in Huajing First Hospital.
"No breathing, the 17th bed volunteers are not breathing!" After the night patrol nurse uttered an exclamation, she ran out, "Go and inform the director, contact Dr. Hu and the laboratory! Go!"
The one who died was a female university student named Zhang Xiaoke from Aviation University. The boyfriend is from the Huaqing Department of Biology, and he admires Li Zheng very much. Every day he mutters that if he is a woman, he must participate in the HPV vaccine clinical trial. Zhang Xiaoke immediately signed up for the clinical trial.
When Li Zheng received the notice, it was about one o'clock in the morning, and he and Zhang Chao rushed over as quickly as possible.
"It has been rescued, and the rescue was ineffective. The death occurred at 0:26." Doctor Hu said gravely.
The face of the official of the drug control department was so dark that water could drip out. The worst case happened. "The cause of death, is it the vaccine?" He asked.
Doctor Hu shook his head, "This alone cannot tell the cause of death."
"Then what should I do, you are doctors, think of a way!"
"Need to solve the plan, right?" Li Zheng, who had been silent, raised his head and looked at Doctor Hu.
Hu Zhongming sighed, "Yes, we need to solve it. We need to get the consent of the family members."
Everyone present was silent for a while. They said that they were able to speak out. A good person came to participate in a drug clinical trial and something went wrong. This person is dead, and they have to plan their corpses. They must be smashed eggs.
"Professor Li, don't worry, since our drug control department has approved this drug for clinical trials, we will take care of it. I have seen the effects of the drug with my own eyes. At most, this matter will delay the time for the drug to be launched." The official of the department is a dare to take responsibility, and he said so.