Chapter 71:

"Sorry, sorry." David waved to Pete Smith insincerely, and then pulled Li Zheng aside.
"Li, you are crazy!" The profit of carbapenem antibiotics is much more than that of paminerazine. He stretched out his arm and drew a big circle in the air.
Li Zheng looked at David, who was constantly making gestures, amused, and patted him on the shoulder, "Don't worry, I am not bad for such a patent." That tone seemed to say, I am not bad for such a dollar.
but! This is not a dollar! It's a patent worth tens of billions!
David looked up and down at Li Zheng, as if looking at an alien. Glancing at Smith and the surprise on his face, he curled his lips and couldn't help but ask again: "Are you serious? If you want, Roche can fight for the rights of carbapenem antibiotics on your behalf."
"David Andorio!" Smith and Kent, who listened carefully to the dialogue between Li Zheng and the two, suddenly raised their hearts. Smith ignored the cleaning of the residue on his clothes and strode towards the two of them.
He gave David a stern look, then turned to Li Zheng with a complex expression, "Mr. Li Zheng, do you mean to give up all rights and interests in carbapenem antibiotics?"
Li Zheng heard the words, and the corners of his mouth slightly aroused, "Mr. Smith, to correct it, I mean I give up all the possibility of obtaining commercial benefits from carbapenem antibiotics. But this does not mean I give up carbapenem antibiotic discovery. One of this identity."
For Li Zheng, who was once a top international scholar, fame is more important than money and profit.
"Of course! This is an indisputable fact!" Smith said loudly. He is not a scholar, he is just a businessman, and patents and profits are what he values ​​most.
Smith did not expect to achieve his goal of this trip so smoothly. This Merck’s tyrant did not hesitate to praise Li Zheng from beginning to end with the most beautiful words of praise. David was stunned when he heard it. He remembers Mr. Smith, who is a stranger who is not allowed to enter and who is inextricable? ?
Smith ignored David's small gesture of winking his eyebrows this time. He smiled and took out a thick agreement from his bag, "Mr. Li Zheng, according to your Xiangjiang people, this mouth is never as good as a pen." Smith said strangely. He pulled a Chinese sentence in a strange tone.
Li Zheng glanced at it. It was his agreement to voluntarily give up the patent rights of carbapenem antibiotics. There are two versions in English and Traditional Chinese. It seems that they have come prepared.
Li Zheng chuckled lightly without procrastinating, took out the pen from his jacket pocket, and signed his name neatly at the place of signature.
Smith's face was even more smiling, and he was about to take over the agreement, but Li Zheng smiled and put the agreement on the coffee table and pressed it with a pen.
"I suddenly thought of something and want to discuss it with Mr. Smith." Li Zheng said.
Perhaps it is the relationship of the contract template. There is an agreement in the agreement that indicates the countries and regions where imipenem plans to be listed in the first batch, such as the United States, Canada, the United Kingdom, France, Italy, and Hong Kong.
There is no China.
Li Zheng only then remembered that imipenem was first listed in the world in 1985, but it was not until 2007 that China had its first imipenem and cilastatin.
For 22 years, Li Zheng did not know how many Chinese people would have to wait for death in despair because there was no imipenem in the country.
"Here, add Hua Guo." Using a pen, Li Zheng added the word Hua Guo after Italy.
Smith and Kent looked at each other, China? The image of China in the hearts of the people of the world in the 1980s was not so good. The country was closed and the economy was backward. In 1979, Premier Deng waved a cowboy hat while watching an equestrian show in Houston, which was interpreted by Western media as a symbol of China's opening up and its efforts to integrate into the world.
A cowboy hat made foreign media so excited, which also reflected from the side how closed and backward the image of China was in the Western world at that time.
"Although China has a large population, their demand for drugs is not large, and the pricing of imipenem is not cheap for them. I have no reason to persuade the business department to open up such a barren market." Smith Said embarrassingly.
Li Zheng shook his head. He pushed hard and pushed the agreement in front of Smith and Kent, "Then I will give you a reason. I..." He pointed to himself, "I am a Chinese. And this Chinese can relieve imipe The method of nephrotoxicity."
From the registration of core patents in 1976 to the listing of 1985, it took nine years. If Li Zheng didn't guess wrong, Merck's drug research team should be stuck at this bottleneck.
"You have a way!" Kent slapped the table and stood up excitedly, "Okay, I promise! As long as the drug is approved for marketing, China will definitely be the first country to list!"
Kent is the head of Merck's research office, and he also named a vice president in charge of research and development. Although he generally doesn't care about things, his right to speak is the heaviest among several vice presidents.
Smith's eyes widened. He was about to speak, but Kent glared back. The head of the laboratory, the president of Flowing Water, Tie Da, does not need to be afraid of Smith as long as his laboratory still has research results!
Li Zheng guessed right, the listing of imipenem was stuck in clinical trials of the drug. Like the carbapenem antibiotics extracted by Li Zheng, imipenem has severe nephrotoxicity. Even because of this, the two drug trial volunteers closed their eyes forever.
In the past nine years, Merck Laboratories has been trying to alleviate nephrotoxicity. In recent years, it has gained some experience, but it is still far from the strict standards of the US FDA.
Hearing that after Li Zheng successfully extracted carbapenem antibiotics, Kent even had the idea of ​​bribing FDA personnel to hide the results of biological tests in order to accelerate the promotion of imipenem.
Of course, if imipenem can be successfully listed on the market through proper channels, that would be the best.
"Be careful. Dean Chen will contact you for specific technical cooperation." Li Zheng said with a smile. He doesn't dispute the patent right of imipenem, but the drug improvement technology is worth a dollar.
On Friday night, Li Zheng’s Interview with People of the Century will be broadcast simultaneously on the BBC.
The outrageous Xiangjiang people saw the young man speaking with his eyes down on the TV show, and the excitement that was aroused by the "Three Questions" of the Xiangjiang Daily gradually calmed down.
After the anger subsided, reason slowly returned.
In this drug-resistant strain infection, the success of Queen Mary Hospital was praised by foreign media, but why did their own newspaper in Hong Kong slept on the six patients who died of infection?
"The risks of using unlisted drugs in clinical practice, the pressure behind this miracle!"
"Characters of the century, a game of life and morality!"
"Trust, the best medicine for doctor-patient conflict!"
On the second day, almost the entire public opinion of Xiangjiang reversed.
"The influence of Li Zheng is really great. Lao Wang called last night and reprinted all the pages he had prepared. The printing factory added a 12-hour night shift, and the newspaper almost opened the skylight in the morning." Shen Wannian said as he said. Put a sliced ​​beef into the mouth.
"Prickly" The piercing noise of tea and porcelain rubbing in the empty restaurant sounded. Yang Wanru frowned tightly and looked at Zhao Qiuhua ill-informed.
Zhao Qiuhua raised his head slightly, passing through Yang Wanru, and placed it on the TV screen not far away. On the TV screen, the familiar face had the calmness and self-confidence she was not familiar with.
"I'm full." Zhao Qiuhua suddenly put down the knife and fork, the collision of metal and tableware was clear and powerful.
Shen Hongji glanced at Zhao Qiuhua's remaining steaks on his plate, and said gently, "If you want to eat more, or if you like Chinese food, it's good to let Sister Liu cook."
Zhao Qiuhua shook his head without saying much, nodded to Shen Wannian and Yang Wanru, picked up the coat on the chair and walked out.
Shen Hongji gave a wry smile, put down the tableware in his hand, and stood up.
"Parents, I'm full, too." After he said, I took my coat and hurried out.
Yang Wanru was anxious, "I'm so angry! It really came from a small place, marrying such an uneducated daughter-in-law really makes me suffer!"
Shen Wannian glanced at her coldly, "When eating, talk less."
Yang Wanru stagnated, and glanced over the daughter who bowed her head to eat and the two empty plates, and her dissatisfaction with Zhao Qiuhua reached its peak.
"Qiu Hua, wasn't it good just now? Why did you get angry again? I know my mom has a bad temper, but this time..." Shen Hongji was helpless.
Shen Hongji and Zhao Qiuhua are college classmates and they met in romantic France. At that time, Zhao Qiuhua was hearty, confident and energetic. She actively participated in club activities, attended gatherings of Chinese students abroad, and participated in the feminist movement. When the rest of the French were still stumbling, Zhao Qiuhua had mastered English, French, German, and even a small amount of Italian. In the mind of Shen Hongji, who was introverted at the time, Zhao Qiuhua was like a goddess.
Shen Hongji had a secret crush on Zhao Qiuhua for two years. Encouraged by his roommate, he mustered up the courage to confess to the goddess. Zhao Qiuhua agreed in one bite. Later, Zhao Qiuhua told him that she had been following him for a long time. Campus love, two-way secret love, the two college romances are passionate and sincere.
But happy time always flies very quickly. Four years have passed in a hurry. One of them wants to return to Huajing and the other to Xiangjiang. The two made an appointment and talked on the phone as soon as they got home to announce their love to both parents.
However, Shen Hongji never waited for this call. Later, China was politically turbulent, and the relationship between Xiangjiang and China was completely cut off, and the two broke off contact.
Until a year ago, when the two met again, Shen Hongji did not hesitate to end his already nominal marriage. Despite Yang Wanru's strong opposition, he insisted on obtaining a marriage certificate with Zhao Qiuhua.