Chapter 365: It's worth these years!


When Li Zheng and Chang Keqing were preparing the next set of samples, Shi Yang and Mo Nian breathed a sigh of relief and completed the "rotating" CT.
Although it is only three minutes, the 3.73G data has already been transferred to the storage array, but at this time these are just some pure high-precision images. To analyze them into three-dimensional structure diagrams, the help of software and algorithms is still needed.
Behind Shi Yang, Liu Tao looked at the small molecules on the screen like a tuft of black briquettes, and couldn't help leaning forward and lifting his glasses.
"Not bad... I took it so clearly the first time..."
"I was also surprised..." Shi Yang also wiped his sweat. "The difficulty of playing with cryo-electron microscopy is mainly in the preparation of sample crystals. As long as the sample purity and parameters are in place, anyone can read the beautiful structure... But this time... It seems to be grind casually?"
Mo Nian nodded and said: "To be precise, it is to grind the progesterone that is available in the Institute of Chemistry casually."
"Wait..." Shen Yiyun next to him was startled, "Isn't this sample carefully prepared by you?"
Mo Nian spread his hand: "Just take it from the consumables."
"Why...why?" Shen Yiyun grabbed his head and yelled, "Our group will make a qualified sample, but it will take ten and a half days to make a bunch of crystals.
"This is different, it is fundamentally different." Mo Nian gestured, "Similar to your conventional electron microscope use strategy, it is still within biological thinking. According to biological thinking, you think that cryo-electron microscope is born to analyze some Rare and complex macromolecular and protein structures, in order to remove interference and analyze the specified information, the requirements for samples are harsh. On the contrary, we only want to look at simple small molecular structures, which can be seen everywhere, and are extremely pure ."
"The gold standard for analyzing the structure of small molecules, shouldn't it be X-ray single crystal diffraction?" Shen Yiyun eagerly gestured, "It is equally difficult to produce qualified crystals."
"That's why we need an electron microscope!" Shi Yang excitedly grabbed Shen Yiyun's shoulders, "The dimension has been upgraded, sister! We have upgraded the chemical microscope this time, from X-ray to CT."
"But... this..." Shen Yiyun even ignored the fact that Shi Yang didn't wash his hands, and only said blankly, "This is too simple... 3 minutes?"
At this time, Li Zheng, who had prepared the next sample, had already walked over.
"It should be 10 minutes." After Li Zheng looked at the screen, he turned to Liu Tao and said, "Next, we will use the Adaboost algorithm to filter out suitable images for 3D construction."
"Hiccup...oh." Liu Tao hiccuped in a panic, "Come on, come with me and use an outside workstation to do it."
"I, I, and I!" Shi Yang jumped up and nodded at Li Zheng with eyes full of attention. Then, without saying a word, he pushed Liu Tao out of the laboratory.
Li Zheng then sat down in front of the console.
"This group does 140° diffraction, rotates 0.5° per second, with a resolution of 0.8?." Li Zheng sighed, moving past his neck and rushing to Shen Yiyun, who was sluggish next to him, "Thank you for your guidance."
At the same time, the leader of the most hip, Lin Moming duo started the preparation of the next set of samples, but in fact the eyes of the two people are always locked on the main body of the electron microscope.
Tu Yi Kou: I have to find a way to dismantle one...
Lin Moming: I have to find a way to buy one...
Just as their third set of samples was placed in the electron microscope, suddenly there was the sound of smashing the glass.
Shi Yang flared his teeth and claws outside, waving frantically.
"Fuck...no..." Shen Yiyun was shocked, and subconsciously glanced at the wall clock, "13 minutes?"
Li Zheng just blew the hair on his forehead and stood up and said: "You stare a little, I'll go out."
"I want to see too!!!"
"Next time, next time."
Li Zheng ran to the door, and as soon as he opened the door, Shi Yang's screams flooded into the interior room.
"Li Zheng from Gan Niang!!! This is what it is!!!"
Upon hearing this, all the people in the back room couldn't bear it, put down the experiment at hand and chased it out.
Only the leader stood still, and secretly moved towards the electron microscope body while they were going out to look at the image.
In the outer room, everyone leaned in front of the workstation screen and squeezed the dazed Liu Tao far behind.
"It's too fast and too easy!!" Shi Yang kept howling at the screen, "X-rays don't necessarily do a good job in half a month. The electron microscope will do it in 10 minutes!!!"
"Ah..." Shen Yiyun stared at the structure picture on the screen that looked like a mole tunnel, took off his glasses and rubbed it vigorously, then looked at it again, "Although it is a bit scribble... but this structure... is indeed progesterone. That's right..."
From the rear, Lin Moming did a lot of hard jumping before he barely saw the picture, but still didn't dare to be too happy, and asked out of breath: "This, this... is really that simple? Why is it so simple that no one found it? We are number one. One?!"
"For the time being...but...it's really too simple." Although Li Zheng was very satisfied with the structure that was analyzed for the first time, he still frowned. After thinking about it, he finally took out his mobile phone and rushed to Shi Yang. "This picture Immediately pass it to Zhou Chenghuan, I have to apply for it in time."
"OK! I'll send an email directly and send the parameters together." Shi Yang's little fat hand, light speed, started to move back and forth between three screens and three keyboards.
...
Forty minutes later.
When Zhou Yi rushed into the laboratory, he saw a dull Liu Tao, a Shen Yiyun thinking about life, a Li Zheng processing data, and a Chang Keqing who was filling out an experiment report.
Everyone didn't care to say hello to Zhou Yi, and Zhou Yi didn't care to say hello to everyone. He just rushed to the screen, grabbed the mouse, and quickly read the analysis images of the three experiments.
After a while, Zhou Yi turned his head fiercely and almost lost his eyes: "Liu Tao, did you see this process with your own eyes?"
Liu Tao was stunned for a while before thinking about starting: "Yes...Yes...It's simpler and clearer than other 100% experiments..."
Zhou Yi immediately fell into a tremor. He tried to straighten his glasses several times and failed. Finally, he threw away his glasses and picked up Li Zheng.
"Oh my God!!!" Zhou Yi clung to Li Zheng's head, his eyes staring with blood, and he couldn't wait to put his forehead up, "How the did you think you could do this!!!"
"Spirit...inspiration is in place..." Li Zheng didn't dare to look at Zhou Yi directly, for fear of forming a ring, "I will disturb you at this time... Mainly considering that this experiment is too simple, even if we don't do it, others will do it. It is only a matter of time. If you want to calculate the results of the Institute of Evolution, I hope you can find a way to buy us some time for laboratory operations."
"Fight!! Must fight!!" Zhou Yi put down Li Zheng, picked up his glasses, stared at Mo Nian, Shi Yang and others who were still performing micromanipulations in the glass window, pointing to it and saying, "Immediately present a simple one. In the experiment report, if the matter is not bad, you can paste the picture. I will take this to pat the Dean’s face and give you the treatment of 7X24-hour electron microscope!!!"
As soon as his voice fell, Chang Keqing in front of the workstation next to him raised his head: "It has been sent to your mailbox. If you need a printed version, I will print it immediately."
Another fierce guy turned his head, and the glasses he had just worn flew out again: "It's only two hours!!"
"To be exact, it's about 1 hour and 10 minutes." Li Zheng leaned over to help Zhou Yi pick up his glasses, "Ah... it's broken..."
"Fuck, it's really troublesome." Zhou Yi took the glasses and simply pierced the broken lens, then put it on in a hurry, and pulled Li Zheng up again, "Go! Kill the dean's house with me!! "
After that, he turned to stare at Liu Tao again: "Xiao Liu, you work hard, today they said you don't leave until the end."
"……Oh."
...
The experiment went smoothly far beyond everyone's imagination. Until 9:40, when Li Zheng sat in the living room of Zhang Shilei, the dean of the Institute of Chemistry, there was still some magic.
In the scientific research circle, although problems such as schooling have been criticized, there is one point that is absolutely superior to all other fields.
That is the leader, he really understands technology.
At least in the science and engineering fields, those in charge of power must have enough academic achievements, and there will never be cases where outsiders lead insiders.
Although Zhang Shilei has not much hair, his appearance is not good, and he is entangled in daily management affairs, his academic ability is still as high as 2482, and his academic qualifications are more than ten thousand higher than Zhou Yi.
Generally speaking, once Li Zheng saw such data, he knew that things were stable.
Sure enough, Zhang Shilei simply asked a few questions, then made a phone call with Liu Tao, and then he escaped into the study and started a series of communications.
According to Zhou Yi's explanation, the current cryo-electron microscopes are mainly used by Hu Zengwu's organic photovoltaic team. If all the recent use rights are assigned to the Li Zheng team, Hu Zengwu must be explained and appeased.
After all, Hu Zengwu is a major subject leader. If he does not nod, even Zhang Shilei will not be able to grab the experiment time.
Although Zhou Yi was determined, he was unavoidable when he thought of Hu Zengwu.
"Oh... if you knew you were training at the time, don't mess with him..." Zhou Yi took off his glasses and muttered while wiping the hollow frame, "Who knew that you would run into..."
"Yeah, who knows this." Li Zheng shook his head and sighed, "It's okay, Dean Zhou, if Professor Hu doesn't agree, we will work overtime at night, and it will be 7pm to 7am."
"Let's not say that you can't carry it, then the laboratory operation and maintenance personnel are afraid that it is not going to uprising..."
"Um... we have a team member who can pay them overtime."
"Ha...Haha..."
"She is serious, and she brought money to the group to solve this unforeseen problem."
"Does this also bring money into the team?" Zhou Yi leaned on the sofa, shaking his head and sighed, "But this can be considered a foresight, if you know in advance that you can achieve this kind of results, it will be so fast... I am afraid it will not be half a circle. People are asking you to bring money into the group."
As he was talking, Zhang Shilei walked out of the study with a look of surprise on his face.
Li Zheng and Zhou Yi quickly got up. Judging from his expressions, the results of this negotiation did not seem to be very good.
"Lao Hu, Lao Hu..." Zhang Shilei kept shaking his head and walked to the coffee table, "Why... just agreed?!"
Li Zheng and Zhou Yi both looked shocked.
Zhang Shilei couldn't figure it out, and said to Li Zheng: "Professor Hu had bitten to death and disagreed, but when he heard your name, he let go, saying that you are a piece of material."
"???" Zhou Yi shook, his glasses lost control again, "Is this the Hu Zengwu I know?"
Zhang Shilei then asked Li Zheng, "Are you friendship?"
"Hmm... I used to go to Teacher Hu's laboratory to help." Li Zheng scratched his head and smiled, "Mr. Hu can do it, he is also the material."
Zhang Shilei was stunned for a moment, looked at Zhou Yi, and the two laughed at the same time.
"Then I must tell Lao Hu."
"It seems that Xiao Li's must be very important."
After sitting down again, the dean's wife also served tea.
Li Zheng wanted to rush back to the laboratory and let the two deans talk, but was forced to stay.
People of different ages and positions will always react and think differently when they see things.
For the two deans, the two hours of data before them have proved that this experiment is bound to have great results.
After finishing Hu Zengwu, compared with Li Zheng's race against time, they had already thought of the next step tacitly.
After a right look, Zhang Shilei put down the experimental report in his hand and watched Li Zheng solemnly place a table on the table: "Li Zheng, according to the judgment of me and Dean Zhou, this is worth one CNS."
Li Zheng didn't have much expression when he heard this.
It must be worth it!
After all, it is the cutting-edge breakthrough content in the system.
The so-called CNS is not a telecom operator, but three scientific publications.
"Cell", "Nature" and "Science".
For most researchers, it is almost everyone's greatest ideal to be able to produce a CNS paper apart from the impractical Nobel.
In other words, a person who has sent CNS is worthy of being called a big shot wherever he goes.
Taking this as the standard of strength is of course a bit pedantic or foreign-oriented.
Unfortunately, this is still the most reliable standard.
Not only reliable, but also valuable.
Almost any influential college in China will receive a bonus ranging from 500,000 to 1 million as long as they successfully publish a CNS paper.
Another regret is that many of the older generation of scientific research workers, due to the limited conditions and resources that year, although they have done a lot of research and contributions, they did not have the opportunity to receive this honor.
On the contrary, many young researchers have become famous at a young age due to the investment of a large amount of resources and the admission of cutting-edge tools such as "cryo-electron microscope".
Non-spoken words, even Zhou Yi and Zhang Shilei in front of them failed to appear on the CNS.
On the contrary, it was Hu Zengwu who made a huge bet in the field of organic photovoltaics and caught up with the times.
"Being famous is to be as early as possible..." Zhou Yi looked at Li Zheng, uncontrollably jealous, "but you kid, it's too early..."
As Li Zheng, he has actually been very restrained. He did not start to correct this until he fully studied at the university level. It was because of the system's compassion for people with disabilities.
"Why..." Li Zheng was indeed a little unbearable, so he asked, "Dean Zhou will be the first author, right?"
"Ah, no, no, that's not what it meant." Zhou Yi hurriedly flinched and waved his hand, "I hardly gave any guidance. It would be nice to hang on the head of our chemical courtyard."
"Okay, Li Zheng." Zhang Shilei also raised his hand and pressed down, "We don't come here in the Chemical Institute. Whoever does the research is whoever does the research, especially Dean Zhou. He has been committed to providing youth There is room for talent growth, you may not realize that Dean Zhou has devoted his efforts to competition and enrollment for decades to welcome the emergence of your seed."
After Zhang Shilei spoke, he raised his teacup aloft: "I see what the young people say now... Zhou Yi, the eternal God of Huajing."
"Forever Dishen!" Li Zheng was said to be energized, and then raised his teacup aloft, "Without Teacher Zhou, there would be no such experiment, Jinghua Jing always Dishen!"
"Don't... don't do it like this..." Zhou Yi reluctantly raised his glass, his eyes were wet red, "but... Dean Zhang really knows me... Seeing you and Shi Yang can grow up... I These years, it's worth it! Cheers!"
"Cheers!"
After the clink, Zhang Shilei and Zhou Yi discussed the next strategy.
Yes, sending CNS requires a strategy...
It was the first time that Li Zheng came into contact with these things.
First of all, as CNS reviewers, they are also human beings, not all-rounders who are proficient in everything.
Especially the reviewers of the first review are not big guys. They are only responsible for initially judging the value of the paper, and the biggest basis is the author of the paper. If the author is a famous guy, it means you can send it directly without looking at it. review.
If you are a lesser-known author, you have to scan a circle and judge whether it is parallel or genuine based on your feelings. Even in many cases, the first reviewer must first Google the author before getting the paper.
Although this kind of judgment is based on rough, it is easy to use. Most people who are not well-known at Google are indeed hitting luck by sending parallel articles.
This is the situation. The so-called mentor resources, academic authority, and nothing else, just putting your name on your paper is already a heavyweight support.
At the moment, the situation of the Li Zheng team is unknown to all members. In order to increase the success rate of the CNS, it is logical to say that a famous boss should be named.
But Li Zheng himself only accepted Zhou Yi's name.
It is a pity that Zhou Yi himself is not well-known in the world. More of his experience has been invested in education.
Therefore, even with Zhou Yi's endorsement, the effect is still limited.
Therefore, we can only use the second strategy-
greet.
The so-called greeting is to call the reviewer by a savvy boss, telling him that there is a good paper and pay attention to it.
This is another embodiment of mentor resources and the authority of scholarship.
Today, the Institute of Chemistry is the most prestigious in the world and has reached the forefront.
It's Hu Zengwu again.
No way, bet on the right direction and you can have everything.
Therefore, what Zhang Shilei meant was that Li Zheng tried his best to cheat Hu Zengwu recently, and of course he will do work in the courtyard, but it is not as effective as he cheats himself.
Regarding this point, Li Zheng inevitably repelled a bit.
"Otherwise, let's publish it in China..." Li Zheng muttered, "Where to publish it or not, it is also very good to improve the level of domestic academic journals."
"No, no." Zhou Yi shook his head repeatedly, "I have said that you have to become famous as soon as possible. As long as you become famous first, everything else will be easy to do. I will tell you, send a CNS out, what are you in school? Resources are all very good, and even if you don’t ask for it, many people will be eager to give it to you. Just take it for the convenience of your future research. First come to the CNS."
"Yes, and..." Zhang Shilei was also unambiguous, and said directly, "This is not just your business anymore. This year, our Institute of Chemistry has not issued a CNS, so it is to help Zhou Yi, help me, and help. The hospital will do this too. Taking a step back, there is a bonus of 500,000 yuan."
"Since the two teachers are so persistent, then I will try my best." Li Zheng sighed, "but I still won't try to curry favor with Teacher Hu, and he doesn't necessarily like it."
"Then go one step at a time." Zhang Shilei said, patting his legs and standing up, "If this is the case, you should get the results out as soon as possible. Zhou Yi and I will review the paper for you when we have time to ensure it Formally meets the taste of CNS."
Li Zheng stood up and said goodbye: "Thank you, Dean Zhang. Since this is our goal, we will try our best to adapt to the format and taste of the CNS."
After a few polite words, Zhou Yi said goodbye to Li Zheng.
Zhou Yi still had a lot of thoughts until he walked out of the cave.
Standing in the yard watching the moonlight, he did not get in the car for a long time.
"Dean Zhou?"
"It's okay, I'll look at it for a while." Zhou Yi raised his head and said, "I need to settle down, I need to settle down..."
"This...this time..." Li Zheng raised his head and looked at the moon with him, "You really should have hosted...I don't mind at all. You deserve it, even if you don't think about it. The experimental resources you have brought are just worth the effort you put on young students for so many years."
"To shut up."
"..."
"Haha, scared, don't say that again in the future."
Zhou Yi turned his head when he said, and put on a Wangwang smile.
"There are so many deans and professors, not all of them are people like me. Some want to win their talents."
"I know that you are very ambitious, and you can even say such things as raising the level of domestic academic journals, but you have to be famous first."
"Only when you are famous, your talent is your talent."
"Only when you become famous can you scare away those who covet you."
"Only when you are famous, you can do the research you want without asking for perfection or seeking resources from people like me."
"For me, a CNS is nothing more than when I go to catch competitions and dig seedlings, those who do not look at my level of scientific research will have to bow their heads and surrender. I don't care about this."
"But for you, a CNS will make you the bright moon in the night sky."
"What Yingpei, what chemical institute, what instructor, you must be accurate."
"To me, icing on the cake; to you, like a tiger with wings."
"So, it must be yours."
Li Zheng was agitated.
I'm about to shout out.
Stop beeping!
A ring, a big ring! Do it now!
"Okay, don't need to say anything." Zhou Yi smiled and shook his hand. "Don't feel owed to me. One day, when someone mentions you, I can tell him with a smile that I dug out this kid Li Zheng. Am I making a lot of money?"
"We have made a lot of money, Dean Zhou, we all made a lot of money!"
"Haha." Zhou Yi smiled, "but I do have a little bit of selfishness, not a request, but a selfish idea. Whether you are satisfied or not will not affect the future."
"But it doesn't matter."
"If possible, let Shi Yang do more work. It is best to be the second author." Zhou Yi shook his head. "My research has always made limited progress... I always think I delayed him..."
"In any case, Shi Yang was originally the second author."
"That's good." Zhou Yi said and opened the car door. "We have made it clear for public and private. The rest... let's hurry up!"
What else can Li Zheng say?
Stare into the car.
"Go! Go on!"
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