Vol 2 Chapter 1616: Biological three-D printer


"First of all, stem cell cloning and organ cultivation technology. The current international research direction is to use mice to conduct experiments and to cultivate relevant human organs and tissues, such as ears, heart, etc., through the intervention of stem cell cloning.
We think that the practical application of this technology is of little significance, so we discarded this research direction, and went straight to the place in one step. How to cultivate mature artificial organ technology in artificial placenta.
This artificial placenta can also be regarded as an artificial organ incubator. Its main principle is to simulate the growth and survival environment of embryos and organs, so as to grow cloned organs from embryos into mature organs.
In this way, as long as the technology is successfully developed, it can be put into the market for commercial use soon. We can build such a biological organ cultivation factory, or we can distribute this artificial placenta or artificial organ incubator to each hospital, and each hospital can independently cultivate it.
In this way, it can greatly provide patients with timely treatment and save more patients' lives. It can also greatly reduce the related costs and reduce the burden on patients.
More importantly, we use stem cell tissues from patients for clonal cultivation. Therefore, the cloned organ that is cultivated is essentially the patient's own organ, so implantation of this cloned organ will not produce any rejection reaction, so the patient does not need to take a lot of anti-rejection drugs after surgery.
And because the fit of its own organs is relatively strong, the patient's postoperative recovery will be very optimistic. "
Hearing Wu Hao's brief introduction, the experts were still surprised. Unexpectedly, Wu Hao and their ambitions were so huge, they actually started directly from the most difficult one.
But think about it, everyone understands Wu Hao's approach. For them, all projects must have market value. Rather than step by step and chasing after a large group of pharmaceutical giants biological research institutes, it is better to take a different path and develop by leaps and bounds.
This direction seems a bit too risky, but once it succeeds, the benefits are huge. The benefits it brings have gone far beyond the economic level and have risen to a higher stage. The significance it brings will undoubtedly be revolutionary and will have a profound impact on all mankind and the future world. Its status in history may be no less than that of humans who invented the computer and the Internet, or even higher.
After letting everyone discuss it for a while, Wu Hao went on to say: "Bio 3D printing organ technology, as the name implies, is the use of biological 3D printing technology to print organs.
Everyone knows about 3D printing technology, and this technology has also been applied to the medical field. For example, many joint replacements currently use 3D printing technology to print related replacement joints.
Compared with the traditional technology, this artificial joint printed by 3D printing technology is printed by scanning the original joint shape of the patient, so the matching is higher and it is more conducive to the recovery of the patient.
And this biological 3D printing organ technology is to use the principle of 3D printing technology to print organ tissues. And in theory, this technology not only prints organs, but also prints various body tissues of the human body. Such as skin, muscles, hands and feet, and a certain part of the body, and so on. "
Ha ha ha ha...
Hearing what Wu Hao said, everyone in the room laughed knowingly.
Wu Hao followed with a smile, and then went on to talk: "The difficulty of this technology is how to use cells to print out living organs.
You know, the development of 3D printing technology is very rapid now, and the development of 3D bioprinting technology is also very rapid. At present, some companies have used bio-3D printers to print out raw meat, and its meat texture is exactly the same as real meat.
However, there is a problem, that is, the raw meat printed by these technologies is dead, not alive. Therefore, these printed raw meat can only be used for consumption.
And what our biological 3D printing organ technology wants to print is the living organ tissue, in layman's terms, it is living meat, not dead meat. We are not using them for cooking, let alone frying steaks, but for implanting them in patients. If it is a dead organ, not only will it not save the patient's life, but it can even bring danger to the patient.
So how to print out the living organs is the core problem we want to overcome. "
Speaking of this, Wu Hao took a drink of water from the cup, and then under the eager gaze of everyone, he went on to preach: "To overcome this problem, then we must start from two aspects.
First of all, we need to prepare the consumables needed for this biological 3D printer machine. This consumable is not available and must be cultivated by ourselves.
Our scientists believe that instead of using allogeneic cells, it is better to directly extract cells from patients for cultivation, and then use these cells to print organs and tissues.
In this way, the printed tissues and organs will not be rejected after transplantation, which is conducive to the rehabilitation of patients.
Therefore, it is still necessary to use cell clone cultivation technology, how to cultivate the consumable cells suitable for the use of biological 3D printer equipment from the cell clones extracted from the patient.
Secondly, what we have to solve is the key to this technology, the biological 3D printing equipment.
The principle and technology of 3D printers are actually not complicated, and the manufacturing is also very simple. At present, the technology in this area on the market is very mature.
But biological 3D printers are a completely new field, not to mention medical-grade biological 3D printers ~EbookFREE.me~ and it is very difficult to print out living organs.
And the consumables to be printed are only a few micrometers and ten micrometers of cells, which requires the entire biological 3D printer to be fine enough to be able to print these tiny cells.
And this has higher requirements for the mechanical structure and system control of the printer, and its accuracy can be no less than that of a lithography machine.
The second is to accurately print each organ tissue, and the more complex the organ tissue, the more difficult it is to print. Although these organs and tissues are composed of cells in different arrangements, this involves the arrangement and combination of cells, so this requires that the printer system must have a sufficient and detailed understanding of the structure of the organs and tissues. It can be printed perfectly.
Although we humans have a very deep understanding of the structure of our own organs and tissues, it will be a very huge systematic project to be accurate to the permutation and combination of each cell. There is no such pharmaceutical giant, medical research institute or even that country. Realized.
So the difficulty before us is very huge. "
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