Vol 2 Chapter 1327: Hatched, my old lady hatched!

   Chapter 1327 Hatched the egg, the old lady hatched the egg!
  A drug, here specifically refers to a compound drug. If you want to enter the clinic, you can learn the scriptures like Lao Tang, anyway, you can’t avoid it.
  The simplest, AIDS clinical trials have failed more than 200 times. The money in it can almost be counted as the endless water of the Yellow River, flowing out. Others, such as herpes, were also unsuccessful.
  Many drugs were seeded before the third period, but in the third period, Quante was a pitted silver gun.
  In layman's terms, the trials before the third phase were all literary dramas, and in the third phase of the clinical trial, this is a real job. Whether it works or not, this thing will be revealed at this time.
  About 10,000 medicinal compounds will be developed a year around the world, and then about 200 to 300 can enter animal experiments, and only more than ten will actually enter the third phase of clinical trials.
  It can be said to be one of ten thousand.
  The test before the third phase is often qualitative. For example, if this thing is eaten, it will cause other diseases. For example, the drug of tea, finds a pair that can make the mice live. This is one of them.
  According to the eight classics, the research is on the treatment of intestinal tumor suppressor drugs. As a result, the skin of the mouse is peeled off. This is a failed chemical synthesis.
What is the third phase trial? The third phase trial simply talks about the toxicology and pharmacokinetics of the first phase, looking at drug toxicity and metabolic mechanism; the second phase, select the dose, through the maximum withstand dose and the minimum effective dose Window, determine the dose of the drug, and initially measure the effectiveness and safety of the drug; the third phase, large-scale effectiveness and safety test, verify that the drug can treat diseases and be used safely.
  After passing these three phases of trials, you can apply for NDA to the regulatory authorities. In fact, there are still four phases. However, the fourth phase is that everyone fools each other. The fourth phase is the market response and some individual requirements of the regulatory authorities. This stuff is fine if you have money.
Therefore, the general medicine instructions allow you to take the measure, you just take the measure, not to mention, there is a gold content in it, but you have to take a handful when you take the medicine, do you think he can’t test it, or you think you Fate.
  Drugs are toxic, especially for some drugs, the window for safe measurement is extremely narrow, and a little more will change from a curative to a murderous poison.
  Before clinical trials, once the drug is qualitatively passed in the laboratory, two appropriate animal experiments must be carried out to provide data for human experiments.
  This thing is a bit more popular, it is to find human cousins ​​who have not appeared in the five clothes to experiment. Although the regulatory authorities of various countries do not specify a certain animal, they have a requirement: animal experiment data related to pharmacology.
  This is so plainly speaking, take the monkey to operate the knife!
  Small-molecule drugs generally require test data for rodent species. Strictly speaking, larger mammals, such as mini pigs and dogs, are generally used.
  As for Zhao Yanfang and the others, they have to use human cousins ​​who have not appeared in five suits, primates!
  So, although I am happy now, the pressure is not small.
  In fact, the current situation is that the Long March has just started, and you will have to die on the Jinsha River if you don’t manage it. The pressure is really not small, but there is hope now!
  So, Zhang Fan now tells himself in his heart that he must hold it firmly, he must hold it firmly, and it must not be swayed. If this is really swayed, the boss of the tea vegetarian government might really cry.
  All the way to the west, on the highway, Cool Luze steadily speeds up, the two ladies are waking up, and those who don’t know think that they both stole corn from someone last night.
   Zhang Fan listened to the Xihai love song of the Phoenix combination, and ran towards the tea all the way.
  After the Tianshan Mountains, the scenery is immediately different.
If you say that the scenery here in Bird City is similar to that of Su Province, except that the land is flatter, it is actually yellowish yellow. The bare hills are like a child with no hair. Just tie up a chicken. Sing the elephant.
  The scenery is different once you cross the Tianshan Mountains and enter the tea plant boundary. The highway shuttles through the Tianshan Mountains, and you can see the snow-capped mountains in the distance. Looking at the white snow in the summer, you can feel a little cooler in your heart. On both sides of the highway are all kinds of cedar trees, lush and lush straight into the sky.
  Really, extremely beautiful.
   Entered the tea vegetarian realm, obviously not home, but Zhang Fan could clearly feel that he was home.
  The two who were put down to make up for sleep, Zhang Fan drove into the hospital.
  ……
  The hospital’s laboratory was overcrowded. Old Chen wiped the sweat from his forehead while looking out. After seeing Zhang Fan’s car, he quickly said:
Zhang Yuan is here, Zhang Yuan is here."
  Except for Ouyang, everyone else is ready to meet Zhang Fan.
  Zhang Fan went into the laboratory and took a look, hey! The leaders in charge of sanitation from the tea plant came, rubbing their hands, it is estimated that the sweat beads are all rolled into pills.
   "If you don't come today, I guess the door here will be squeezed." Ouyang looked at the group of people around him unwillingly.
   "The report, I will look at the report first."
   Zhang Fan asked quickly.
   "I'm in charge. Before you come, the report is sealed and no one can read it first." Ouyang said.
   "Take it out, Zhang Yuan is here!" The leader in charge of health is like a junior high school student waiting for the video studio owner to show the midnight movie, and he is quite dissatisfied with Ouyang.
  After a while, the report was brought over, and Zhang Fan found an office. After entering, he opened it and prepared to take a look.
   Ouyang whispered to Zhang Fan: "The security of the laboratory is probably out of order."
   "It's not necessary, it's not clinical phase III yet." Zhang Fan didn't understand.
  "What do you know, something is going to happen, you can’t even cry for crying. Look at how complicated people come and go in this place.
  Maruko country, Golden Retriever country, golden mean, digital, and doctors from various places to experiment, some not, do you know what people think? "
  Ouyang said that, Zhang Fan felt that the old lady was right. There is a real problem, who is he looking for to cry.
   "Okay, you are right, let the tea vegetarian government come forward?"
   "No, we are not related to Luhang, okay, our plane, they borrowed it last time, I mean let Luhang send one to come over!"
   "Uh!" Zhang Fanhan came down. Ouyang's tone was too loud. A company, a small hundred people, you haven't done anything yet, you just want a company. If you want to be able to do something, do you have to move to the Chasu Hospital in the Frontier Military Region?
   "Okay, okay, okay, I'll let Lao Chen contact you later. You can use as little as you want, and save the critical moment."
  Zhang Fan soothed the old lady, the old lady was very useful!
  Opening the report, Zhang Fan felt a little painful. He read the report too hard this time. It was almost all in English and there were a lot of chemical formulas.
  The head is big!
  (End of this chapter)