Chapter 179:
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Back To The Age Of The 80s
- 大河自西
- 1876 characters
- 2021-03-03 07:49:29
After the most difficult time passed, the following things became more and more smooth.
After three courses of treatment, there have been enough data to prove the clinical effect of erlotinib, but at the same time, its side effects have also appeared.
"Comprehensive data show that erlotinib is suitable for the third-line treatment of locally advanced or metastatic non-small cell lung cancer where two or more chemotherapy regimens have failed." Li Zheng made a final summary.
"Yes, it's a pity, we don't have enough time, otherwise we should do more for the TKI of EGRF." Ruiz couldn't help but sigh.
"Of course, the launch of erlotinib is only our first step, and the discovery of EFRF represents countless possibilities. However, this data is enough for us to convince those diehards to accelerate the development of the human genome project."
Although the clinical performance of erlotinib is not amazing, it does make up for the lack of the drug market for advanced patients who have failed chemotherapy. For many people who have clinically declared that they have no therapeutic significance, it is the only one. A life-saving straw.
So its market significance is great.
The family members and the medical staff of the state hospital looked at the patients who had been lying in the beds for a long time and could not go to the ground. They were almost crying with joy when they were finally able to walk under the medication.
That sense of accomplishment made Li Zheng feel exhausted from his continuous work.
"Li, this is the charm of clinical practice. Sometimes it makes you reluctant to step into the laboratory, and sometimes it makes you feel that everything you do is valuable and sacred." Ruiz stood at Li Zheng said beside him.
Li Zheng smiled bitterly, "Fortunately, the result is good, otherwise, I am afraid I will really choose to escape." Executioner and savior, their work hovered between the two, for the victory of mankind, there must be sacrifices. The awe-inspiring words, he has studied countless times in textbooks, but when it comes to the truth, he can't say anything.
The collective and the individual are always full of contradictions and paradoxes. No one can demand that the individual must make concessions for the collective, no one.
Ruiz patted Li Zheng on the shoulder, and all the experimenters on this road had to face each other. He used to be, and so is Li Zheng now.
"I think we should go to Cold Spring Harbor, Watson and the others should have prepared afternoon tea for us."
As Ruiz once said, now Cold Spring Harbor has become their frequent place.
The red lecture hall, once regarded as a sacred place by many international colleagues, sometimes became a place for them to argue or even argue.
When Li Zheng and the others arrived, Watson and others were already waiting in the office.
Watson saw the two of them and stood up suddenly from his seat. "It's done?"
"It's done!" Li Zheng and Ruiz nodded at the same time.
Watson and Berg looked at each other, with ecstatic expressions in their eyes. They had been entangled with those diehards for more than half a year in order to advance the Human Genome Project. Now the emergence of Erlotinib is an opportunity. They have waited for half a year.
Li Zheng handed Watson and Berg the two thick piles of drug and clinical data.
Watson and Berg are also not welcome. Once their prestige has reached their level, they don't care whether to avoid suspicion.
The two quickly flipped through the information, and the joy on the face became more and more intense. Although erlotinib is not a perfect drug, it does realize the first targeted drug today. It not only fills in the late stage non-small cell lung cancer after chemotherapy has failed. The blank of drugs has opened up a new way for humans to fight cancer.
"What about the patent, is it registered?" Watson asked, looking up.
"The patent application has been submitted." Ruiz said.
"Okay!" Watson nodded, "I believe our genome project can really begin soon!"
The next is a long time for wrangling. The American scientific community suddenly became lively. There were related reports one after another, and members of Congress blushed and quarreled.
Under the influence of Watson and others, the FDA has accelerated the approval of the listing of erlotinib.
And Li Zheng also admitted that he had done everything he could do, and after saying goodbye to Watson, Ruiz and others, he embarked on the road to return to China.
Of course, before returning to China, he had already talked to Watson about participating in the Human Genome Project. As a participant in the meeting of experts of the Human Genome Project and someone who has made great contributions to the promotion of the project, no one can question Li Zheng’s right to participate in this project. Li Zheng and Li Zheng’s team are important members of the Human Genome Project research group. , This is already an established fact.
"This plan requires the extensive participation of all countries in the world. As a populous country accounting for one-fifth of the world’s population, China is a country with a large population. From a scientific point of view, we welcome China’s participation. But Li, you know, politics will always It's very ugly, I can only promise you to do your best." This is Watson's original words.
Li Zheng didn't say hello in advance when he returned to China this time. When he saw that there were only two Huaqing students in the lab, he raised his eyebrows, and those little boys actually dared to be lazy when he was away.
"Li...Professor Li." A Huaqing student said tentatively.
Li Zheng threw the bag in his hand on the sofa, "Where are Meng Jie and Sun Bin?"
"Mr. Meng and Ms. Sun have gone to the Academy of Sciences." The Huaqing student thought for a while and added, "Academician Tian asked them to go."
Li Zheng smiled, Meng Jie, Sun Bin and the others were actually called teachers. As for the fact that they were called to the Academy of Sciences by Tian Lao, Li Zheng could also guess something.
That day, after Mr. Hetian and the others said that he could only guarantee that his team’s people would participate in the Human Genome Project, Mr. Tian and others were silent for a while. Li Zheng understood their feelings, and on the one hand, for the Chinese scientists to participate in this. I am delighted in this project. On the one hand, a few little kids can feel resentful because I and others cannot participate.
But in the end, they put the glory of the country in front of them, that's why Meng Jie and others went to the Academy of Sciences.
Li Zheng nodded, "I got jet lag after I went, and they came back, go to the room to call me." He ordered this, and walked back.
By the time Meng Jie and the others came back, it was already close to seven o'clock in the evening, except for the three of them, Zhao Depei, Tian Lao and Yang Lao.
This is the first time that Mr. Tian and Mr. Yang have entered the Ninth Laboratory.
This equipment is much better than our Academy of Sciences. No wonder the experimentation methods of these two boys are so rough. With such equipment, the requirements for hand skills are much lower.
The three of Meng Jie bowed their heads and did not speak, like roosters that had been defeated in a fight. They had been drilled by Mr. Tian and Mr. Yang these days. They finally knew how lenient Professor Li was to them.
The two Huaqing students were also clever. When they saw a few people coming in, they rushed to the villa behind to meet Li Zheng, so when Li Zheng came over, they just met with a few people.
"Professor Li!" Sun Bin had the sharpest eye. He saw Li Zheng as if he had seen some kind of savior. He ran over quickly, and Li Zheng avoided Sun Bin's open arm on his side.
"Speaking of which, don't be so excited." Li Zheng showed a helpless look on his face, "Principal, two seniors, sit down."
He pointed to the sofa beside him and said.
It is the first time for Tian Lao and Yang Lao to see Li Zheng and have heard Professor Li's very young words countless times, but when they really saw this young man in a denim T-shirt, they were still a little bit sad.
"The waves behind the Yangtze River push the waves ahead. Professor Li is really a heroic boy." Tian Xiangjun couldn't help but smile.
Li Zheng waved his hand, "Tian Lao, you are polite, Tian Lao is our model, the founder of Hua Guo Biology."
Tian Xiangjun shook his head, "Let’s stop complimenting each other, let’s talk about the subject. I heard that at the beginning of the year, the U.S. Department of Energy and the National Academy of Medicine allocated 5.5 million US dollars to build a laboratory. The news of the Human Genome Project is buzzing. You can give me a word. Will this project start within this year?"
Tian Xiangjun also made some efforts after the talks with Li Zheng last time. Although China's economy in 1987 was developing steadily, there were too many places to spend money in such a large country. Compared with biological sciences, the country More willing to invest money in visible military industry.
Tian Xiangjun mobilized almost all his contacts and explained to the leaders the importance of the Human Genome Project over and over again. At the end of last month, someone in the center finally let go.
But this year's national scientific research budget has been allocated, and China will put the human genome project on the agenda in the next few years.
"Yes!" Li Zheng said directly without hesitation.
Before he left the United States, biologists headed by Watson had basically convinced the US Congress that as long as the laboratory was completed, the Human Genome Project would be officially launched.
"I see." Old Tian looked a little depressed.
In this life, because of Li Zheng's intervention and the advance launch of anti-cancer targeted drugs, people around the world have truly felt the huge power hidden in their genes.
Compared with the Human Genome Project that was successively carried out by various countries in the previous life, this time the Human Genome Project presents a blooming situation.
Italy, the United Kingdom, the United States, Germany, and France have initiated projects and have a tendency to unite, which makes the Chinese scientists excluded from the system even more anxious.
When the United States announces the official launch of HGP and the integration of resources from various countries joins in, this will be the most difficult time for the Chinese biological circle.
It's just that Li Zheng is powerless.
Project cooperation must be exchanged on an equal footing. Today, China has no basis for human genetic research, let alone strong financial support. Governments of various countries will not agree to China's participation in this project.
What Li Zheng can do now is to let Chinese scientists headed by himself participate in the project, and open an opening in this project team composed of major countries in the world, so that the ability of the Chinese government to participate in the future will no longer be the same as in the previous life. That's hard.