Chapter 360: Biological cell factory

Seeing that the synthesizer has been started, the result may take a long time.
Zhang Zhi and they all sit beside to rest, waiting for the synthesizer to give the final result.
This instrument caused Li Lingqiu's curiosity and she entered the scientific research management interface of the company's management space.
Find detailed data of this synthesizer. Especially its operation principle.
It is divided into two parts, the most important of which is the synthesis of genetic material.
The synthesizer obtains the base pair sequencing of DNA, and Star Blue controls the nanorobot in the instrument to synthesize single-stranded DNA.
This is a nano robot specially designed for gene synthesis. They carry various biological enzymes for biochemical reactions.
After the synthesis of single-stranded DNA, under the action of DNA transcriptase. Synthesize another piece of DNA.
The two DNAs form a double helix structure, and then give them the beginning of transcription. Add the DNA single-stranded label that provides the template. Transcription start area, end area.
Finally, let them form a ring-shaped, stable structure.
A piece of DNA that can exist stably in nature is completed.
The other part is the synthesis of proteins.
In the last part, the DNA that can be expressed is transcribed into a single-stranded RNA under the action of RNA transcriptase.
Put RNA into this instrument,
There are more than 30,000 ribosomes, which are screened out, the ribosomes with the lowest survival requirements, and their efficiency is very high.
It can synthesize a polypeptide chain according to the base information of RNA.
Under the action of biological enzymes and nanobots. Synthesize a biologically active protein.
After Li Lingqiu read it, he admired the company's technology workers very much.
With this synthesizer, future research in life sciences will be simplified a lot.
"The result came." Ding Ling shouted excitedly, attracting everyone's attention.
The light curtain also shows the newly made photosynthesis.
Under an electron microscope millions of times, it looks lifelike.
It is shaped like a big spindle, big on both sides and small in the middle. It is surrounded by a biofilm in vitro, with protein channels and protrusions on it.
Li Lingqiu showed a look of surprise, Zhang Zhi felt that it was a bit magical.
Ding Ling and Lin Congshan, they are not surprised, they have expressed other proteins many times.
Lin Congshan saw that the instrument had successfully synthesized photosynthesis. He turned to prepare the solution for the experiment for a while.
Ding Ling sighed and said: "I don't know if this photosynthesis, there is the effect that Director Li said.
I have never heard of it, it can stably exist in animal cells and has a photosynthetic cell structure. "
Li Lingqiu said confidently: "Wait a moment, you put this photosynthetic gene all the way into the animal cells, and you know what I said is true."
Lin Congshan took over the experimental equipment and solution, he said: "Can this photosynthesis convert ADP to ATP, if it can succeed. We will open a new page in biotechnology."
Zhang Zhi saw that the three of them were operating. As a common sense thing, he knew what ATP was.
ATP scientific name adenine nucleoside triphosphate, referred to as adenosine triphosphate.
It is an unstable high-energy compound composed of 1 molecule of adenine, 1 molecule of ribose and 3 molecules of phosphate groups. Also known as adenosine triphosphate.
Almost all living things, the energy they need for their activities are directly provided by ATP.
It contains high-energy phosphate bonds. After the hydrolysis, a large amount of energy that can be directly used by the organism is provided.
ATP hydrolysis generates ADP and a phosphate group. After ADP absorbs energy, it will synthesize ATP. They are recycled in the organism.
ATP is produced by photosynthesis and the respiration of all cells.
The essence of photosynthesis is to directly store light energy through chemical energy. For use by organisms.
Lin Congshan shook the small bottle in his hand and said, "There are ADP and phosphate groups. There is no ATP.
As long as the presence of adenosine triphosphate is detected in the experiment, we can prove that this photosynthesis can really play a role. "
They turned on the synthesizer, extracted a large amount of photosynthesis from them, and put them into the reaction vessel.
And illuminate them with an appropriate light source to complete all preparations. Everyone waited for the results of the experiment.
The waiting time is anxious, but the result of the waiting is gratifying.
The speed of photosynthesis is very fast, and the detection of the sensor is also very sensitive.
Soon, the presence of adenosine triphosphate was detected in the solution.
There was a look of joy on their faces, and Lin Congshan said in disbelief: "This is amazing, really amazing."
Ding Ling said in surprise: "What a miracle in the biological world, our knowledge is still too short. I thought I designed a few days ago that only a few million base pairs of DNA can survive life.
That's enough for me to rejoice. I never expected to encounter photosynthesis, such a magical biological structure. "
Li Lingqiu repeatedly checked the experimental data several times. She said: "This photosynthesis, although not like the chloroplast, can only synthesize adenosine triphosphate.
It cannot produce substances such as sucrose like chloroplasts.
But it is also magical enough, the most important thing is that it can exist in animal cells. The chloroplast cannot be implanted in animal cells. "
Zhang Zhi saw them finish the experiment, he stepped forward.
"We just discussed so much about the use of this photosynthesis. Now we should choose a cell and experiment whether it can survive in the cell."
Ding Ling said embarrassedly: "Zhang Zhang, we just talked about the application method of photosynthesis.
This is an imagination of future plans ~ EbookFREE.me ~ It is not yet officially available. It is mainly aimed at animal cells. Generally, higher animals have an immune system in their bodies.
For abnormal substances like photosynthesis, the immune system clears them outside the cell. The lysosomes are directly triggered within the cell, clearing the entire cell. Unless using viral means. "
Zhang Zhi frowned and said: "Then you talk about animals that grow photosynthetic cells in the epidermal cells of pigs, cattle, sheep and other animals, and grow meat only in the sun.
These magical animals who only drink water but do not eat, this kind of vision cannot be done now. "
Li Lingqiu exclaimed: "Every new thing comes out, we have to give him time to develop."
"I think there is a cell that can fully adapt to photosynthesis." Lin Congshan said suddenly.
Seeing the eyes of everyone inquiring, he said his own vision.
"The cell I am talking about is a cancer cell. We can extract cancer cells from a mouse.
Then send this DNA into cancer cells.
Cancer cells have the characteristics of infinite reproduction, and their surface is smooth and bulky. Its own lysosome has no effect.
We now use it to produce most antibodies and biological detection agents. For example, our common pregnancy test stick is realized by this technology.
We can completely transform cancer cells into a biological cell factory.
After it is added to photosynthesis, as long as there is a light source and basic materials are added, it will be produced continuously. "
Zhang Zhizan sighed: "This method is very good, it is cheap, and the technology is not complicated."
He opened his brain wide and said: "You should not be limited to animal cells, bacteria and fungi, and plant cells. Maybe after implantation of photosynthesis, greater changes will occur.
Hearing his words, Ding Ling and Lin Congshan did not fluctuate, and their faces were very tangled.