Vol 2 Chapter 1852: come, come, come, listen to me

  Where will the future medical care of mankind go? Zhang Fan had never considered this issue before. At the beginning, Zhang Fan was thinking about how medical care could make him food and clothing, so that he could buy a house and marry a daughter-in-law.
   Later, when all of this was done, Zhang Fan would occasionally think about it, and then wait for the level of surgery to reach the second-level requirements of the system, which is already the peak level in reality, and then Zhang Fan really began to think about it.
   Maybe it's because Zhang Fan is just a layman, but this is more representative of the mentality of the majority of medical professionals. Just like every ordinary doctor in every hospital, if you ask where medical care will go in the future, he will definitely wait for the mortgage to be paid off! Doctors are also ordinary people, but the society has given him more moral requirements.
   As for the future of medical care, in fact, Zhang Fan's answer now is that the future of medical care will definitely move towards replacement surgery. Many doctors say that the future will be minimally invasive and interventional. Zhang Fan definitely does not agree with it. Minimally invasive and interventional at most are just reducing the size of the current surgery. Combined with the apoptosis factor in human cells, the future medical treatment is definitely replacement surgery.
From the perspective of the human heart, with the increase of interventional operations, there are more and more disadvantages, especially under the brutal promotion of commercialization, the disadvantages are hidden. The 10-year blockage rate has become an important part of interventional operations that have to be faced. 's subject. Of course, the benefits are also obvious.
   In the system, Zhang Fan quickly went through the cardiac surgery operation. The operating room was ready, just waiting for Zhang Fan to open his eyes for the operation.
   "Zhangyuan!" Director Lin glanced at Zhang Fan worriedly, he thought Zhang Fan was too tired
   "It's okay!" Zhang Fan shook his head.
   And the four students were already muttering in their hearts, "Is this a special trick to close your eyes before surgery?"
  Extracardiac surgery is quite laborious compared to general orthopaedics.
   Orthopedic surgery, general surgery, it doesn't matter if you cut a little more, such as a swollen appendix! But it’s different outside the heart. To a certain extent, the operation outside the heart requires more refinement than the operation outside the brain. The operation outside the heart is not to mention one more knife, and sometimes one more needle may be fatal.
   Zhang Fan, Director Lin, and the former deputy director of the extracardiac director. The four of them were on the operating table for a whole morning. The extracardiac surgery should not only have good technique, but also good equipment and materials.
   "The valve material needs to be replaced!" When replacing the valve, Zhang Fan said something inexplicably.
   Director Lin was stunned for a while, and the first thought in his mind was: This material is sunshine! The equipment representative is a man! Then I thought: This is not advanced?
  Valve, what is this thing, it is actually a window.
  The heart is like a suite of four house prices. The door is the aortic valve, the mitral valve and the tricuspid valve are the windows, and the blood is the air, which is probably what it means.
   If you talk about it in detail, it will be more troublesome. The initial perfusion volume and fluid movement are really troublesome.
  Some people have said that if you want to understand the liver, you should be better at chemistry and biochemistry, and if you want to understand the heart, you should be better at physical electrophysiology.
Replacing windows, not to mention the heart, is a more troublesome thing even for ordinary people, and there are currently three types of valves, one is mechanical valve, and the material is often titanium, because this is the only thing that does not affect the autonomic nerve. Metal material, the second is the heart valve of pigs and cattle, and the third is the intervention umbrella type.
   Zhang Fan is using a mechanical valve today. What can I say about this device? It has obvious advantages and disadvantages. It is necessary to take anticoagulant drugs for life. Even if it is taken for life, it is easy to form blood clots near the valve.
  After the operation, Zhang Fan said hello and left in a hurry. Director Lin felt that Zhang Fan was very strange today.
   Zhang Fan started to call as soon as he left the operating room, "Ms. Zeng, I am Zhang Fan, do you have time now? If so, please come to the administrative building."
  Ms. Zeng was originally in a meeting, and one of the busy ones wished to become three, but on Zhang Fan's phone, she was having afternoon tea in a leisurely manner.
  Zhang Fan immediately called Zhao Yanfang again. Old Zhao was very honest. He was busy nursing the baby.
   In the administrative building, Wang Hong raised her chest and took Zhang Fan's four students, standing at the door waiting for everyone in the meeting.
   After a while, Ms. Zeng arrived first, and was seen by others
Early   , the Kung Fu family specially changed into a set of clothes, Maoni's coat was a black lace skirt, and the small boat-toed shoes under the feet showed the black silk instep at the neck of the neck.
   When Zhao Yanfang came, everyone was there.
   "The current heart valves have their own advantages and disadvantages. I have an idea, can we invent a product that combines all the current clinical advantages and has fewer disadvantages."
As soon as    said this, Lao Zhao began to frown.
"The biggest drawbacks of all valves in the clinic are relatively large turbulent stress (which can cause fatal or semi-fatal damage to red blood cells and platelets) and larger pressure gradients and reflux volumes than normal heart valves. If only To deal with anticoagulation or increase the time of use, if there is no pressure on the cost, I think it can still be taken seriously."
   Lao Zhao heard that he supported Zhang Fan, but when he thought about it carefully, he was against it. People say there is a level, which means that you can't change the biggest drawback, so don't do it. It's a waste of money. If you have this money, you might as well give it to me!
  Ms. Zeng sat there quietly with a smile as if she had come to a lady's afternoon tea, and there was no superfluous expression on her face.
   She knew that at this time, she had better be a little transparent. If she said something inappropriate, Zhang Fan wouldn't be able to hit it with a hammer.
  The turbulent flow speaks human words, that is, the blood in the blood vessels has swirls, and there are red blood cells in the blood. This thing carries oxygen. This product is the same as the face of a big-faced cat. It is a disc, and it is also very delicate.
  When turbulent flow occurs, these things rub against each other and collide with each other, and the big face plate will break. Once broken, it will lose the function of transporting oxygen.
Many diseases can lead to turbulent flow, such as the unruly heart beating, and the bouncing rubbing turns into bouncing rubbing. At this time, there will be countless turbulent flows inside the heart, causing blood to not flow out of the heart, and the effect of the defibrillator is, A slap in the face woke up the heart and made it start to rub.
   In the past, Zhang Fan never thought about developing any equipment. First, he didn't have time, and second, he didn't have technology.
It is different now. In order to avoid the parent company interfering with their business too much, or to avoid letting others gossip, several large companies jointly established a new company, which was registered in China, and the hospital also took a stake. company, which is equivalent to its own company.
   And Zhang Fan needs such a new company now. They come up with their own ideas, they come up with technologies, and finally they work together to produce products. Otherwise, if you cooperate with these old capitalist companies, you will not know how you will die.
   Is there such a company in China? Yes, but it can be seen from the valve market that Huaguo is still not good at this aspect. For example, biological membranes are commonly used in valves in Europe and the United States, while mechanical membranes are commonly used in China. From this point, Zhang Fan can only use chickens to lay eggs.
   "Hehe, I think so too, don't think about it if you don't have money, Ms. Zeng is an expert in this regard."
  Zhang Fan smiled and said something to Lao Zhao, then looked at Ms. Zeng. With an embarrassed smile on her face, Ms. Zeng said it was not okay to say no, and it was not okay to say yes. Really, she now feels that Zhang Fan is getting harder and harder to serve.
   Lao Zhao pouted, Zhang Fan turned his head and said to Wang Hong, "Prepare a non-disclosure agreement."
  Wang Hong is now a generalist, from uploading and distributing to business classification, and now even knows a little about legal affairs.
   "What the do you want to do? It's so exciting." Old Wang asked curiously, but Zhang Fan didn't speak.
Ms. Zeng spoke first: "Currently, Medtronic and St. Jude's mechanical valve products occupy more than 80% of the global artificial valve market, but now Abbott and Edwards Life Sciences biofilms have surpassed Medtronic. The biggest advantage of biofilms is that they don't need to take anticoagulant drugs for a long time, but bio-attenuation is their flaw."
   Zhang Fan nodded, Zhang Fan didn't know who had the most market share.
   But what Zhang Fan understands is the length of these two instruments.
   Signed the agreement, and it was done in a while. After Wang Hong went out with the legal affairs of the hospital.
  Fan Zhang started, "I now have an idea to manufacture the next generation of heart valves with pure pyrolysis carbon combined with biology."
  Bioprosthesis
  What does the biodegradation of the membrane mean? To put it simply, if you keep your finger in your mouth for a little longer, will the finger turn white and the skin will fall off? That's what it actually means.
The heart valve needs to be tightly sutured, there is a little gap, just like a middle-aged man peeing, it is no longer a straight line, it starts to fork like a flower wine, and it makes sense to urinate a little accidentally. .
   Zhang Fanyi said, Lao Zhao's face wrinkled like a rag, "I'm not very familiar with this piece."
  Zhang Fan was overjoyed, Nima finally has something you don't understand, but he didn't show it on his face.
   "Today is a ventilation meeting, I mean you first form a team, you need some people from materials to mechanics and biology, and they must be cutting-edge talents.
   After the team is formed, I will take out the paper. "
   Ms. Zeng said with a puzzled face: "Pure pyrolysis carbon was popular for a while at the beginning, but after everyone left the biological item, this one was put on hold."
   "Yes, my idea is not pure pyrolytic carbon, but the coupling of pyrolytic carbon and biological valve!"
   Zhang Fan is reluctant to say more, because in the system, all valve devices are pyrolytic carbon and biologically coupled valves. So Zhang Fan is not afraid of going the wrong way.