Chapter 467: : Not too good news

Hughes Medical Research Institute, one of the most famous non-profit medical research institutes in the United States, the global bioterrorism outbreak, under the coordination of WHO, Hughes Medical Research Institute, became the 'angel team' to tackle VFV virus specific drugs Institute.
Qiu wants to lead a few people from the team and walk towards the conference room.
Qiu thinks that there is a report in the hands of the VFV antibody research report, but there is not much happiness on the faces of everyone.
The patient's serum or body fluids are used to treat viral infections, which are the most common moves. During this period of time, their team found that the antibodies in the patient's serum were too weak to clear the VFV virus.
And they can't find a recovery patient. The VFV virus is too toxic, and the antibodies produced by the human body's immune system simply cannot 'kill' the virus.
This led to the study of their specific drugs, nothing to do.
After discussion, the team decided to try the animal immune serum, and found 8 animals to experiment, let the animal infected with the virus, but soon found that even the immunized bovine serum had no obvious effect on the treatment of VFV.
During this time, I experimented every day and tried hundreds of possible ways.
Try all the possible conjectures they discussed, and finally find that the most successful ones are monoclonal antibodies.
In order to speed up the research, the 72-person team was divided into eight groups, four groups were responsible for finding other therapeutic drugs, and the other four groups were responsible for testing the 16 monoclonal antibodies, and the group led by Yau was one of them.
At the time of testing, the four groups of people used 1000 times of LD50 (half the lethal dose) to poison the experimental mice.
Within 24 hours after exposure, mice were injected with monoclonal antibodies, four groups of 16 monoclonal antibodies, and 11 remaining; 48 hours, 5 antibodies were still effective; 72 hours, only two antibodies were effective.
It was an antibody that he led the first group to study, and an antibody that was studied by a third group led by British medical scientist Judson.
Two of these antibodies were found, and they started experimenting with rabbits. Both antibodies were effective for 24 hours. After 48 hours, the ability of monoclonal antibodies began to show significant differences, many lost their activity, and the time was long, the role of antibodies Getting weaker.
The incubation period of the VFV virus far exceeds this time, and such antibodies are simply not available for treatment, and the study is once again stalled.
Finally, after discussion among the people, it was decided to use the 'cocktail' method of eBoR special drug research, using the best four monoclonal antibodies mixed, using a virus that can produce human interferon as an adjuvant for "cocktail" antibodies. Let 'Cocktail' also work after 72 hours of exposure.
The ‘Cocktail’ pharmacy was named Ag72.
Now, the results of the Ag72 test are in the hands of Qiu.
Looking at the report in his hand, he was not happy because the results were different from what they imagined.
When Qiu and Judson entered the conference room, they felt that dozens of eyes fell on them. Many researchers on the field didn't look very good. Since the formation of the 72-person team, some progress has been made in their research, but the progress is not great. Now I hope that they will all be in the report of Qiu and Jia Desen.
"Come on." Yau wanted to hand the report to Judson.
"You come." Judson shook his head and did not reach out.
Qiu nodded helplessly. When everyone sat down, let the assistant send the report in his hand to every researcher on the field and walk to the position of the podium.
"The results of the monoclonal antibody test came out, and we were different from the results we predicted. We tested the effect of Ag72 with two rhesus monkeys. On the fourth day of infection, the monkeys developed symptoms and were given Ag72 as planned. But unfortunately, the virus in the monkey did not disappear, VFV did not cure." Qiu thought heavy.
There was a sigh in the conference room, and many experts shook their heads and frowned.
Monoclonal antibodies are the most promising direction in a short period of time. If a monoclonal antibody fails, the specific drug will take longer.
The number of people infected with the VFV virus has reached more than 26,000 worldwide, and the number of people is refreshing every day. The number of deaths has soared to 2,378. There is no cure for the time being. If the treatment does not come out, it means that the number of deaths will increase.
"But there is a good news that is not too good."
Everyone instantly lifted his spirits and raised his ears to wait for the answer of Qiu.
"Injecting Ag72 monkeys within a week, the condition did not deteriorate further. Ag72 can not cure the condition of VFV, but can inhibit the metabolism of VFV and control the disease to further deteriorate. This result can give more treatment time for the disease. ""
Many people on the field were applauding and cried. At this time, any little good news is exciting news.
The 'Angel Team' made a breakthrough in VFV virus specific drugs and successfully developed monoclonal antibody agents that inhibit the deterioration of VFV.
The news was released, as if it was mad, it spread throughout the world, attracting all the people.
Now is the most serious period of the VFV virus. At the time of global panic, the biological virus almost reached the critical point of complete out of control. At this time, the 72-person team sent good news, which is undoubtedly the most exciting time.
This victory in the fight against biological warfare has already dawned.
When the outside world cheered for the results of the 72-person group, the other corner had the same happy event.
River Microbiology Medical Research Institute.
Xu Minsheng had a rare smile on his face.
Jianghe Company and Lanhong Pharmaceutical were merged into the army ant group and reorganized into Jianghe Pharmaceutical. He became one of the team leaders of Jianghe Pharmaceutical Pharmaceutical Development and was responsible for the development of tumor vaccine.
The current Jianghe Pharmaceutical Headquarters is the main microbiology medical research institute of Haixing Company. The main medicines of Haixing Company are all developed from here.
Some time ago, Chen Mo contacted them, told them a research direction, and gave them some information, so that their research team can make data related drugs, drugs may reduce the activity of VFV virus, and help VFV treatment.
Now is the most terrible time for the VFV virus to be raging. With the order of Chen Mo, the entire research team immediately convened personnel to start developing drugs.
The team concentrated on the strength of the elites of the entire institute, and thoroughly read the information that Chen Mo gave, and the shifts were studied and finally progressed.
During the period, he contacted Chen Mo several times and asked questions about the research direction. After several major breakthroughs, he finally completed the required medicine according to Chen Mo’s meaning.
They gave the developed drug, named HX3.
Nowadays, the VFV virus in the culture dish has a markedly reduced metabolic activity at 24 hours after the addition of the HX3 agent, and the drug has reached the requirement of Chen Mo.
"Successful." Xu Minsheng showed a rare smile.
"Successful." Several researchers around him also nodded and vomited a deep breath.
"You will sort out the report and hand it over to the boss. I will ask the boss what to do next to HX3." After that, Xu Minsheng turned and left the lab.