Chapter 32: Carcinogenesis


   Huang Ji’s top priority is undoubtedly improving his medical skills and prolonging grandpa’s life span.
   In the next time, he decided to devote himself to medical skills and physiochemistry, and strive to find a way to save his grandfather as soon as possible.
   His learning goal is to be the top medical professors in the entire magic city.
   Deputy Dean Lu Qinggong, is a professor of pathology at Fudan University and the most powerful surgeon in the affiliated hospital.
   Half of the master and doctoral students in the hospital were brought out by him. They are Fudan's favorite doctoral supervisors to take students. There are always several graduate students under his name every year.
  Its comprehensive ranking of medical skills is less than 3,000 in the world, and it is studying the latest academic papers and improving surgery every day. It can be said that it is at its peak.
   In the morning, he will participate in a seminar to discuss a plan for a patient with lymphoma and several chief physicians.
   When most of the people arrived, Huang Ji was well dressed, Shi Shiran walked into the meeting room and closed the door easily.
   He was holding twenty printed data files, came to everyone's seat lightly, and placed the files in front of everyone on the table.
   No one doubted him, and one of them nodded at him.
   Huang Ji finished delivering the documents and sat silently in the seat next to the projector.
   Lu Qinggong sat in the main seat, but stared at Huang Ji for a while, and said strangely: "Who are you?"
Huang Ji quickly stood up, bowed and smiled slightly: "Dean Lu, I am Professor Yang Qizhong's student Huaxu, something happened to Sister Xiaoqian's house temporarily, and the phone is out of power, so I can only temporarily entrust me to work. She has forwarded the patient's information to me. She said that the patient's previous diagnosis and treatment records in Zhongshan Hospital have been sorted out, and it is behind page 27."
   Wow, everyone turned to page 27, and the results are the patient's previous medical records in other hospitals.
   "The medical advice of Professor Zhang from Zhongshan Hospital has also been sent. Sister Xiaoqian said that she put the second sheet in the attachment."
   Lu Qinggong stared at the information, nodded, and waved his hand and said: "Um... well, I see, you can sit down."
   "By the way, do you understand the meeting process?"
   Huang Ji said: "Understood, I have also been a mentor's meeting assistant before."
   "Hmm..." Lu Qinggong didn't say much, after asking everyone to read the information, they started the discussion.
When discussing the details of the spread of the patient’s lymphoma, he was about to remind Huang Ji that it was time to put the projection on, but saw that Huang Ji had already snapped the projection on the screen. Not only that, but it also happened to be what he was discussing with everyone. A partial scan.
   Lu Qinggong was very satisfied, so he didn't say much, and continued his analysis.
   As the research progressed into better conditions, Lu Qinggong gradually got used to the existence of Huang Ji, and he almost forgot that there was an assistant beside him.
   Because whenever he needs something, Huang Ji will carefully prepare what he wants.
   The entire meeting was extremely smooth, without any small flaws that interrupted thoughts.
   When the plan was finalized and the meeting was about to end, Lu Qinggong suddenly realized that Huang Ji, an assistant, was better than any graduate student he had seen!
   is almost completely integrated into it, as if he has also participated in the discussion. Only by knowing what everyone is discussing anytime and anywhere can he show the information he wants so seamlessly.
   "You are good, what is your name?" After the meeting, Lu Qinggong smiled and greeted Huang Ji to come over.
   "Huaxu."
   "Well, Yang Qizhong's graduate student, right? I think you have a good understanding of the condition just now. Are you also researching the subject of cancer?" Lu Qinggong asked with a smile.
   Huang Ji said: "Yes, I am thinking of a drug to co-stimulate immune lymphoid T cells to block the pd-L1 binding on the surface of cancer cells."
   "Huh? Are you studying this?" Lu Qinggong was startled.
   He thought Huang Ji was just studying a small topic, but he didn't expect it to block the recognition of cancer cells by immune cells.
  The key to a chronic disease of cancer cells is that it can mimic a protein recognition pathway of normal cells, allowing immune cells to recognize themselves as normal cells. If a drug can be found to block this disguised recognition, the body's immune system will spontaneously attack and kill cancer cells.
Lu Qinggong said: "This topic is too big for you. I don't understand it at all. I only found out after reading the latest paper. RB is conducting research in this area. The domestic pharmaceutical conditions are still a bit worse. I also think about this occasionally."
   "Using the human immune system to kill cancer cells is recognized as the best way to combat cancer in the world."
   "If this medicine is developed, even if it can't cure all cancers, it will win the Nobel Prize!"
   Huang Ji smiled and said, "I don't think this is the best way."
   "Oh?" Lu Qinggong was surprised.
Huang Ji earnestly said: "The essence of cancer is genetic mutation. It is a mismatch that occurs during the process of cell replication and division, which breaks the Hayflick limit. There are too many cases that can cause this gene mutation. Viruses, fungi, chemicals, ionizing radiation, and even ultraviolet rays, and family genetic carcinogenesis. What is more difficult to prevent is that there are cancers caused by mental stress and life pressure."
   "Isn't this an organism's adaptation to the external environment? Some changes are made in the form of genetic mutations, and even such genetic mutations can be written into genetic material."
   "In the final analysis, it is indeed a disease, because the infinite reproduction of cancerous cells will destroy normal organs and tissues. But if you look at it from a macroscopic perspective of species evolution, this can also be called an evolutionary process."
  "The reason why immune cells judge cancer cells as normal cells may not be because cancer cells are ‘cunning’ and learn this disguise for their own survival. But this is a kind of normal biological evolution, natural evolution!"
   Lu Qinggong was stunned. He had never heard such strange talks.
  Cancer is an evolution? Should the immune system allow them?
   He excitedly said: "What are you kidding? Once cancer cells spread, how high the mortality rate is? Do you know the destructive power of cancer cells is destructive, what evolution is this? Does it evolve people to death?"
   "The mortality rate of cancer is indeed high, but it also has a rare phenomenon of'self-healing'." Huang Ji said.
   Lu Qinggong frowned. Indeed, there have been many self-healing cases of cancer throughout the ages.
   There are often some cancer patients, the symptoms disappear naturally, and the cancer cells disappear inexplicably. And this kind of self-healing patients, UU Reading www.uukanshu.com often does not relapse.
"Natural selection, survival of the fittest!"
Huang Ji said:
Both animals and humans will suffer from cancer. This is not a disease unique to humans. The theory of evolution advocates neutral mutations and natural selection. This is correct, but it is incomplete and cannot explain all phenomena. Three kinds...cancer evolve!"
"This is a malignant mutation. For the short-term and individual of a species, it is indeed a disease with a very high mortality rate. But the human civilization is only a few thousand years? The birth of mankind is only a few hundred thousand years? From the perspective of the macroscopic evolution of China, the significance of this malignant mutation may be positive."
"Of course, human beings are civilized and intelligent, so they can take the initiative to make unnatural changes. Today's medical methods use various drugs to suppress cancer cells, surgically remove unspread tumors, and also want to block "Friendly recognition" of cancer cells by immune cells."
   "These methods, of course, can save people and allow individuals to survive. But judging from the evolution of the entire human species, the current thinking on cancer in the world may be stifling human evolutionary potential."
   Lv Qinggong said angrily: "You still take biology? I have taught you two doctors, but this is the first time I have seen you who are as rebellious as you."
Huang Ji smiled and said, "Ahem...I know that the purpose of medicine is to save people. I just can't help but say that it is not the best way to contain, remove, and eliminate cancer cells. , Leading cancer positively to complete the positive mutation of human genes, and letting it disappear by itself after'great success' may be the best treatment idea.
   "Not only has cancer been cured, but humans are also taking another small step on the path of adapting to evolution."
  ……
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