Chapter 191: Patent attribution

Office of Cryptococcosis Institute.
"Hello Zhou Zuo, it has been a long time since I met with God, and today I finally saw a real person."
"Haha, it's the same! I have long admired you, Director Zhang, and I have always wanted to visit you, but unfortunately I haven't been able to make a trip."
Zhang Wen shook Zhou Wen's hand and said with a smile: "If I knew you would go to Zhonghai last time, I said nothing would go on a business trip."
Zhou Wen laughed loudly, "That won't work. If you delay your work, then you are guilty."
Although the two people are more than 20 years old, they both hit it off at first sight and sympathized with each other. The chat was quite speculative!
In addition to the titles that are well-known to the public, Zhang Wen, like the director of the Department of Infectious Diseases of Huashan Hospital, the director of the Department of Internal Medicine of Fuluo University School of Medicine, and a doctoral supervisor, he has another identity-a biomedical researcher of Fuluo University.
Don't underestimate the identity of this biomedical researcher. Zhang Wen's main focus is microbiology.
All his achievements can be said to come from microbiology.
"Well, Zhou Wen, don't patronize Zhang Wen, let me introduce to you, this is Pan Renfeng, director of the Department of Infectious Diseases at Harmony Hospital."
"Hello, Mr. Pan..."
In the morning in the laboratory, Zhou Wen did not have time to get to know each of these big guys.
Unlike the domestic academic magnates who are busy engaging in political life, those who come today are all academic leaders who are really working on the front line.
Everyone is very follow-up and approachable.
After a simple greeting, everyone's topic naturally quickly focused on the neutralization effect test.
Everyone had a lively discussion.
...
...
The Cryptococcosis Research Institute of Jiangzhou Hospital, the news of the successful isolation of antigenic B cells spread like wildfire.
Once the news came out, it immediately attracted the attention of the domestic medical community.
Before the domestic medical community had reacted, the latest news revealed that it was not only as simple as a successful isolation, but was successfully amplified and expressed antibodies.
This time, it is not just that simple to pay attention, but to start to inquire about the truth.
But at this moment, Jiangzhou Hospital announced that the antibacterial cells had passed the neutralization test.
One stone caused a thousand waves!
Everyone can't sit still now.
Through the neutralization effect test, in other words, the next step can start clinical testing. As long as there is no rejection or major side effects, it can be officially launched as a Cryptococcus neoformans vaccine on the market.
This is incredible news.
According to the latest research of the Proceedings of the National Academy of Sciences of the United States, infections caused by neoformans cause about 1 million deaths worldwide each year, of which about 600,000 are in sub-Saharan Africa.
Cryptococcus neoformans enters the human body mainly through the lungs and can be distributed throughout the body, including the brain.
The result of the infection is cryptococcosis, which can cause chest pain, dry cough, bloating, headache, blurred vision or confusion. This infection can be fatal, especially if there is no antifungal treatment.
Even with treatment, the mortality rate is as high as 30%.
It's terrible!
Soon, health organizations in many countries called and even the World Health Organization called for consultation.
In addition, some large pharmaceutical groups and research institutes have also called in one after another, asking about the technology to isolate antigenic B cells...
The successful replication of antibacterial cells is of great significance.
...
While the global medical community is paying attention to this matter, Jiangzhou University School of Medicine and Tanzhou University School of Medicine are also discussing with Zhou Wen about the patent attribution of some technologies.
At the beginning of Jiangzhou Medical College, Zhou Wen did not expect to replicate antibacterial cells successfully. The main purpose was to use Zhou Wen's influence on prions to increase the influence of Jiangzhou University School of Medicine.
The same is true for Tanzhou Medical College. In fact, the goal is the same. It is the best to succeed, and to earn academic reputation if it fails.
But never expected Zhou Wen to succeed.
There is really no place to make sense.
Now that it has been successful, there is no need to say more about the halo honor, but they are all superficial things.
But the issue of core interests is also very important.
That is the issue of patent attribution.
In the anti-cryptococcosis vaccine, at least 5 to 10 patented technologies are involved, each of which can bring long-term and huge benefits. This must be stated as early as possible to avoid unnecessary disputes in the future.
Although Zhou Wen was unwilling to talk about such a naked thing as soon as the results came out, there was no way. The leaders of the two universities were anxious, so he had to come.
Meeting room, Medical Department of Jiangzhou University.
Chen Tongguang, director of the medical department, said: "Professor Zhou, you are the main person in charge of the project, tell me your opinion!"
Zhou Wen said straightforwardly: "Okay, then I will talk about my opinion.
The Cryptococcal Disease Research Institute was established with the support of your leaders, and the two parties had an agreement before, so I think it will be fine to distribute according to the agreement.
After the follow-up vaccine clinical trials and marketing, 90% of the costs and benefits will be shared equally between Jiangzhou University and Tanzhou University, and the remaining 10% (excluding clinical trial costs) will be shared by all our experimental staff distribution. "
Lu Yongfeng, director of the School of Medicine of Tanzhou University, asked: "Of course we know this. What about other patents?"
Zhou Wen said strangely: "What patents are there?"
Lu Yongfeng smoked a cigarette and said, "Cell isolation technology, amplification technology, measurement technology, and primer design data, etc., should all these be counted?"
Zhou Wen glanced at Chen Tongguang and asked, "Director Chen, is this the result of your discussion?"
Chen Tongguang said with a helpless expression: "This is not the meaning of the Ministry of Medicine, it was proposed by the school."
Zhou Wen nodded and said: "Okay! Then I'll just say it, except for vaccines, all the other patented technologies are owned by me personally. I made it clear when I was the deputy director of the institute at the beginning. And it’s written in black and white in the contract."
Lu Yongfeng smoked a cigarette and slowly said, "You can't say that! The contract belongs to the contract, but you can't ignore the facts.
The vaccine was indeed researched under the leadership of Professor Zhou, but in this process, other researchers have also put in hard work and sweat. You can’t take all the benefits by yourself, and others have nothing, right? ? "
Zhou Wen frowned, "What makes me take all the benefits by myself?
Without me, does Director Lu think that antigenic B cells can be isolated?
Without me, does Director Lu think sequence amplification can be successful?
Without me, does Director Lu think a vaccine can be developed?
We must respect the facts and conscience when we speak, let alone ignore the facts! "
Seeing that the atmosphere in the conference room was a little stiff, Secretary Liu from Tanzhou University who came to preside over the negotiations smiled and said, "Professor Zhou, don't be angry and listen to me.
Vaccine research is a good thing. There is still a lot of work to be led by Professor Zhou. Let’s talk calmly. "
After a pause, he said: "You see if this will work, let's take a step back. Professor Zhou can take out the separation technology and amplification technology, and you will own the rest."
Zhou Wen smiled and said, "Secretary Liu, do you think it is possible?"
After a pause, Zhou Wen followed: "When you, Director Cheng and I, asked for Cryptococcus mutans serum, I gave it without saying a word. Later, your Xiangya Hospital successfully cured Cryptococcosis neoformans and won countless honors and applause.
But I was criticized for this, and the bonus was deducted!
Later, your Xiangya Hospital wanted to set up a Cryptococcal Disease Research Institute, and I specifically asked me to be the first person in charge of the project. I didn't want to, and it was your leaders who repeatedly invited me before I agreed.
It also agreed to transfer 90% of the proceeds to both medical schools.
Now let me take a step back.
I'm sorry Secretary Liu, I can't take this step back today. "
Said Zhou Wen stood up, "Why don't you follow the contract, or you can sue me!"
After talking, Zhou Wen turned around and left, leaving a room of people looking at each other.
...
Jiangzhou Hospital Testing Center, PCR group.
In the office, Zhang Shuguang, Yang Liqun and Wang Huiyao are chatting.
Because Zhou Wen left, Zhang Shuguang couldn't find a successor, so he has been concurrently the leader of the PCR team.
As for Wang Huiyao, he and Yang Liqun are good friends, and came here to see him today.
"It's a pity that kid is gone." Zhang Shuguang said, smoking a cigarette.
Yang Liqun smiled and said, "I don't think it is a pity! If he is still in the PCR group, how could he have grown to where he is now?"
Wang Huiyao also smoked a cigarette and said with emotion: "Yes! His talent in biology is something I have only seen for so many years, and it is unprecedented."
Yang Liqun said: "I think it's normal! The vast majority of geniuses are juvenile fame.
For example, Newton was only 24 years old when he discovered the three laws, the law of universal gravitation, and calculus, Einstein was 28 years old when he discovered the theory of relativity, and Schrödinger was only 26 years old when he proposed the theory of relativity. Who else is there? "
Zhang Shuguang continued: "Heisenberg discovered an uncertain relationship at the age of 26, Bohr proposed the hydrogen atom model at the age of 28, and Josephson predicted the Josephson knot at the age of 24."
Wang Huiyao nodded and added: "Anderson seems to have discovered positrons at the age of 22. The youngest Nobel Prize winner is Little Prague, who seems to be only 21 years old."
After Wang Huiyao finished speaking, Yang Liqun followed: "Also, Maxwell was 24 when he discovered the laws of electromagnetics."
Zhang Shuguang said: "You said ~EbookFREE.me~ why is this?"
As soon as his voice fell, Zhou Wen's laughter came from the open office door, "Because when a person receives a large amount of cutting-edge knowledge in the shortest time, he is most likely to discover.
At this time, the constraints are small, the thinking is quick, and the most critical and useful information can be found from a large amount of intricate information.
And if you use a step-by-step approach, you may gain a lot. Each knowledge point is well-founded and logically rigorous, but at the same time, thinking inertia is generated, it is difficult to make breakthrough discoveries!
As we age and experience more and more, there will be less and less thinking.
Because in many cases, experience can replace thinking. In this way, there will be fewer and fewer problems. Problem solving always depends on experience first. In the end, new problems will basically not be raised, and there will be no new discoveries..."
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